Metabolic syndrome and atherosclerotic risk factors as determinants of blood sugar control in diabetic patients: a retrospective cohort study.

Objective: To examine the effects of metabolic syndrome and atherosclerotic risk factors on blood sugar control in diabetic patients.

Material And Method: This present retrospective cohort study of two hundreds of medical records of diabetes patients treated at the outpatient internal medicine department during the year 2006-2007. Data were collected using a case record form containing biochemical profile characteristics of patients and metabolic components by the World Health Organization (WHO) criteria.

Effects of statins vs. non-statin lipid-lowering therapy on bone formation and bone mineral density biomarkers in patients with hyperlipidemia.

Introduction: The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, named statins, are well-established cholesterol-lowering drugs able to reduce cardiovascular risk in hypercholesterolemic patients. The possible effect of statin on bone tissue, so-called pleiotropic effects has received particular attention. Studies reported a positive effect of statin on bone tissue in both of animal and human study by enhancing the expression of the bone morphogenetic proteins (BMPs), in particular of BMP2, which in turn leads to osteoblast differentiation and bone formation including interfering with osteoclastic activity.