Publications by authors named "Susum Yokota"

Article Synopsis
  • Lead exposure is toxic and particularly harmful to the central nervous system, but its specific effects on brain microstructure and function had not been thoroughly studied before this research.
  • The study analyzed data from 920 young adults, revealing that higher levels of lead in hair samples are weakly linked to changes in brain activity during memory tasks and alterations in the brain’s white matter structure.
  • Participants with increased lead levels also showed poorer performance in cognitive tests and higher impulsivity, suggesting that even low levels of lead exposure can have subtle but significant effects on brain function and behavior.
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Zinc is a biologically essential element and involved in a wide range of cellular processes. Here, we investigated the associations of zinc levels in hair with brain activity during the n-back working memory task using functional magnetic resonance imaging, fractional anisotropy (FA) of diffusion tensor imaging, and cognitive differences in a study cohort of 924 healthy young adults. Our findings showed that greater hair zinc levels were associated with lower brain activity during working memory in extensive areas in the default mode network (i.

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