Development of a model for registration and notification of accidents and incidents in nuclear medicine.

Nuclear medicine (NM) is a medical speciality that uses unsealed radioactive sources involving several handling procedures with some critical points before, during, and after the examination and therapies performed, requiring special attention to the occurrence of a possible accident or incident over the course of the clinical routine. The accidents and incidents in NM can involve actors such as workers, patients, the public or caregivers, and even the environment. Although expected, the number of occurrences and their nature are not well understood due to the absence of a Brazilian reporting tool for incidents or accidents.

SPECT performance evaluation on image of Yttrium 90 - Bremsstrahlung using Monte Carlo simulation.

Yttrium-90 (Y) is one of the most widely used radionuclides in Nuclear Medicine practice. However, characteristic energy of this beta emitter constitutes a difficulty for dose planning using SPECT imaging. This work aimed to study bremsstrahlung X-rays effects produced by Y beta particles during SPECT image acquisition using Monte Carlo code MCNPX.

A cost-effective way to reduce the equivalent eye lens dose fromYttrium-90 radiopharmaceuticals.

Purpose: We analyzed the effect of the use of Eye Protective Equipment (EPE) and the best position to use individual dosimeters to estimate the eye lens radiation dose to a medical staff that works with yttrium-90.

Methods: Three Alderson-Head-Phantoms were exposed to 58MBq of Y for 24h, in two different experiments: (1) at different dosimeter placements and (2) with and without the use of EPE. The measurements were carried on by thermoluminescent technique.

Individual dose planning in radiosynoviorthesis treatment: Step by step.

Radiosynoviorthesis (RSO) is a minimally invasive treatment aiming for the necrosis of the pannus tissue by the use of radionuclide. The method suggested here starts with the segmentation of the joint effusion, synovial thickness, and area of the synovial membrane using the 3D Slicer software. The last step is the estimated value of the activity to be injected without considering the leakage of the radiopharmaceutical into the articular cavity.

Outpatient treatment for haemophilic arthropathy with radiosynovectomy: Radiation dose to family members.

One of the key features of good practice in medicine is the doctor-patient communication. Radiation protection standards for radiosynovectomy (RS) is limited. Yttrium-90 is a beta-emitting radioisotope used in RS to treat joint pain from haemophilic arthritis.

Genotoxic and cytotoxic effects of testosterone cypionate (deposteron(®)).

The indiscriminate use of anabolic androgenic steroids (AAS) has motivated researchers to investigate the mutagenic action of these substances. The present study, using the mouse bone marrow micronucleus test, evaluates the genotoxic potential of testosterone cypionate (deposteron). Male Swiss mice received intramuscular injections of deposteron at three doses.