Publications by authors named "Susi Sadler"
Objectives: To evaluate potential return on investment of the National Health Service Diabetes Prevention Programme (NHS DPP) in England and estimate which population subgroups are likely to benefit most in terms of cost-effectiveness, cost-savings and health benefits.
Design: Economic analysis using the School for Public Health Research Diabetes Prevention Model.
Setting: England 2015-2016.
Background: The United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) was the biggest ovarian cancer screening trial to date. A non-significant effect of screening on ovarian cancer was reported, but the authors noted a potential delayed effect of screening, and suggested the need for four years further follow-up. There are no UK-based cost-effectiveness analyses of ovarian cancer screening.
View Article and Find Full Text PDFBackground: Fragility fractures are fractures that result from mechanical forces that would not ordinarily result in fracture.
Objectives: To evaluate the clinical effectiveness and safety of bisphosphonates [alendronic acid (Fosamax and Fosamax Once Weekly, Merck Sharp & Dohme Ltd), risedronic acid (Actonel and Actonel Once a Week, Warner Chilcott UK Ltd), ibandronic acid (Bonviva, Roche Products Ltd) and zoledronic acid (Aclasta, Novartis Pharmaceuticals UK Ltd)] for the prevention of fragility fracture and to assess their cost-effectiveness at varying levels of fracture risk.
Data Sources: For the clinical effectiveness review, six electronic databases and two trial registries were searched: MEDLINE, EMBASE, The Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, Web of Science and BIOSIS Previews, Clinicaltrials.