Effects of immediate or delayed addition of platelet additive solution on the in vitro quality of apheresis platelets.

Background: There is little knowledge how different hold times of hyperconcentrated platelet (PLT) suspensions (HPSs) before the addition of platelet additive solution (PAS) might affect PLT quality. We compared the in vitro quality of single-donor PLT concentrates (SDPs) with immediate or delayed PAS addition and studied the quality of collected concurrent plasma (CP).

Study Design And Methods: We collected 6×10(11) PLTs in 175 of mL plasma and CP from 31 donors.