Publications by authors named "Susanne T Nonekowski"
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Synopsis of recent research by authors named "Susanne T Nonekowski"
- Susanne T Nonekowski's research primarily focuses on the enzymatic activity and structural biology of tRNA-guanine transglycosylase (TGT) in Escherichia coli and its interactions with various substrates, including RNA and DNA.
- Her studies reveal critical insights into the mechanism of TGT, highlighting key residues like aspartic acid 143 that are pivotal for substrate recognition and modification processes.
- The findings suggest that TGT not only modifies tRNA by exchanging guanine with the modified base queuine but also possesses the capability to recognize and modify DNA, broadening the understanding of its biochemical functions.
