Supervised Obesity Reduction Trial for AF ablation patients: results from the SORT-AF trial.

Aims: Weight management seems to be beneficial for obese atrial fibrillation (AF) patients; however, randomized data are sparse. Thus, this study aimed to investigate the influence of weight reduction on AF ablation outcomes.

Methods And Results: SORT-AF is an investigator-sponsored, prospective, randomized, multicentre, and clinical trial.

Development of carbon plasma-coated multiwell plates for high-throughput mass spectrometric analysis of highly lipophilic fermentation products.

Classical approaches to strain improvement and metabolic engineering rely on rapid qualitative and quantitative analyses of the metabolites of interest. As an analytical tool, mass spectrometry (MS) has proven to be efficient and nearly universally applicable for timely screening of metabolites. Furthermore, gas chromatography (GC)/MS- and liquid chromatography (LC)/MS-based metabolite screens can often be adapted to high-throughput formats.

Interactions affecting the bioavailability of dietary polyphenols in vivo.

Polyphenols are widely abundant dietary constituents in plants that are associated with health-promoting effects. This review summarizes factors influencing the bioavailability of polyphenols, specifically flavanols, flavonols, flavanones, flavones, and hydroxycinnamic (phenolic) acids. Most factors tested so far indicate that bioaccessibility, defined as the amount of compound reaching the enterocyte in a form suitable for absorption, is the most important factor determining the absorption in the gut.