Synopsis of recent research by authors named "Susanne Mende"
- Susanne Mende's research primarily focuses on the mechanisms of cardiovascular and liver diseases, exploring how various treatments, such as angiotensin inhibitors and beta-blockers, impact these conditions in animal models, particularly in relation to the effects on vascular resistance and liver fibrosis.
- A key study demonstrates that Angiotensin-(1-7) treatment can reduce vascular resistance in apolipoprotein E-deficient mice, suggesting potential therapeutic options for managing endothelial dysfunction associated with atherosclerosis.
- In addition, Mende has contributed to understanding mitochondrial disorders, particularly MELAS syndrome, by profiling gene expression and identifying regulatory protein networks that may influence disease manifestation, highlighting the complex relationship between mitochondrial function and nuclear gene expression.
