Publications by authors named "Susanne L Rasmussen"
Article Synopsis
- This study aimed to evaluate if hs-CRP, NT-proBNP, and suPAR could predict cardiovascular outcomes more effectively than traditional risk factors in younger and older individuals without existing cardiovascular disease.
- Conducted with 1951 participants from the MONICA study between 1993-1994, the study categorized subjects based on age and sex and followed them for an average of 18.5 years, focusing on deaths from cardiovascular causes.
- Results showed that NT-proBNP was linked to cardiovascular death in almost all groups except younger women, while hs-CRP and suPAR had specific associations, but none of the biomarkers improved risk assessment beyond traditional factors, with NT-proBNP enhancing reclassification mainly in men and
Aims: The aim of this study was to examine whether high-sensitivity C-reactive protein (hs-CRP), N-terminal pro-brain natriuretic peptide (NT-proBNP), and soluble urokinase plasminogen activator receptor (suPAR) carried incremental prognostic value in predicting cardiovascular morbidity and mortality beyond traditional risk factors in apparently healthy individuals.
Methods And Results: This was a prospective population-based cohort study comprising 1951 subjects included in the 10-year follow-up of the MONItoring of trends and determinants in CArdiovascular disease (MONICA) study, between 1993 and 1994. The principal endpoint was death from cardiovascular causes.
Central blood pressure (BP) estimates the true load imposed on the left ventricle to a higher degree than does brachial BP. Increased aortic pulse wave velocity (aPWV) and central BP are risk markers for cardiovascular disease. Both can be measured by simple and noninvasive methods.
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