Investigating the Mutagenicity of a Cold Argon-Plasma Jet in an HET-MN Model.

Objective: So-called cold physical plasmas for biomedical applications generate reactive oxygen and nitrogen species and the latter can trigger DNA damage at high concentrations. Therefore, the mutagenic risks of a certified atmospheric pressure argon plasma jet (kINPen MED) and its predecessor model (kINPen 09) were assessed.

Methods: Inner egg membranes of fertilized chicken eggs received a single treatment with either the kINPen 09 (1.