Outcome of bleomycin electrosclerotherapy of slow-flow malformations in adults and children.

Objectives: To evaluate the safety and clinical outcome of bleomycin electrosclerotherapy (BEST) for treating extracranial slow-flow malformations.

Methods: In this retrospective investigation of a multicenter cohort presenting symptomatic slow-flow malformations, patient records were analyzed with respect to procedural details and complications. A treatment-specific, patient-reported questionnaire was additionally evaluated, obtained 3-12 months after the last treatment, to assess the subjective outcomes, including mobility, aesthetic aspects, and pain, as well as the occurrence of postprocedural skin hyperpigmentation.

CT-guided interstitial brachytherapy of primary and secondary lung malignancies: results of a prospective phase II trial.

Background And Purpose: CT-guided interstitial brachytherapy of primary lung malignancies and pulmonary metastases represents a novel interventional technique, combining conventional high-dose-rate (HDR) iridium-192 ((192)Ir) brachytherapy with modern CT guidance for applicator positioning and computer-aided 3-D radiation treatment planning. The purpose of this study was to assess safety and efficacy of this technique.

Patients And Methods: 30 patients with 83 primary or secondary lung malignancies were recruited in a prospective nonrandomized trial (Table 1).

CT-guided interstitial brachytherapy in the local treatment of extrahepatic, extrapulmonary secondary malignancies.

The purpose was to evaluate the safety and efficacy of high-dose-rate (HDR) CT-guided interstitial brachytherapy in the treatment of extrahepatic, extrapulmonary, secondary malignancies. Nineteen patients were included in this prospective study. The median age was 66 years (49-77).

Eye imaging with a 3.0-T MRI using a surface coil--a study on volunteers and initial patients with uveal melanoma.

MRI of uveal melanoma using 1.5-T technology and surface coils has developed into a standard procedure. The purpose of the study was to evaluate the feasibility of 3.

CT-guided interstitial single-fraction brachytherapy of lung tumors: phase I results of a novel technique.

Purposes: To assess the safety of CT-guided brachytherapy of lung malignancies and to evaluate the initial therapeutic response.

Patients And Methods: Fifteen patients with 30 lung malignancies were included in this prospective phase I trial (metastases, 28; non-small cell lung cancers, 2). Pre-interventionally two patients had a vital capacity of < 80% (39% and 63%).

In vivo assessment of the tolerance dose of small liver volumes after single-fraction HDR irradiation.

Purpose: To prospectively assess a dose-response relationship for small volumes of liver parenchyma after single-fraction irradiation.

Methods And Materials: Twenty-five liver metastases were treated by computed tomography (CT)-guided interstitial brachytherapy. Magnetic resonance imaging was performed 1 day before and 3 days and 6, 12, and 24 weeks after therapy.