Publications by authors named "Susanne D Otto"

Article Synopsis
  • Neoadjuvant therapy (NT) is a standard treatment for locally advanced rectal cancer, and endoscopic vacuum therapy (EVT) is used to address anastomotic leakage after rectal surgery.
  • A study analyzed 243 patients who underwent rectal resection, finding that 19.3% experienced anastomotic leakage requiring EVT, with 61.7% of these patients receiving NT.
  • Results showed no significant differences in EVT duration, healing time, treatment failure rates, or ostomy reversal between patients who received NT and those who didn't, indicating that NT does not negatively impact EVT outcomes.
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(1) Surgical site infections (SSIs) are a relevant problem with a 25% incidence rate after elective laparotomy due to inflammatory bowel disease (IBD). The aim of this study was to evaluate whether stricter hygienic measures during the COVID-19 pandemic influenced the rate of SSI. (2) This is a monocentric, retrospective cohort study comparing the rate of SSI in patients with bowel resection due to IBD during COVID-19 (1 March 2020-15 December 2021) to a cohort pre-COVID-19 (1 February 2015-25 May 2018).

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Purpose: The aim of this study was to evaluate both the feasibility and effectiveness of sacral neuromodulation for fecal incontinence and constipation in adult patients who had undergone surgical repair of anorectal malformations (ARM).

Methods: Patients with ARM with or without sacral dysgenesis who presented with fecal incontinence, constipation, or combined symptoms were treated with sacral nerve stimulation (SNS). Success of SNS was assessed by scores preoperatively and after a 3-week test period: Cleveland Clinic Incontinence Score (CCI), Surgical Working Group for Coloproctology (CACP) continence score, German version of the Fecal Incontinence Quality of Life Scale, and Cleveland Clinic Constipation Score (CCCS).

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Background: Anorectal manometry is used extensively in the assessment of patients with disorders of the pelvic floor. The present study investigated the repeatability of anorectal manometry in healthy volunteers and patients.

Patients And Methods: A total of 30 healthy volunteers (15 men and 15 women) and 10 patients with fecal incontinence (4 men and 6 women) underwent perfusion manometry and volumetry.

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Purpose: Sacral nerve stimulation (SNS) can improve fecal incontinence, though the exact mechanism is not known. This study examines the following hypotheses: SNS leads to contraction of the pelvic floor, influences rectal perception, and improves continence and quality of life.

Methods: Fourteen patients with sacral nerve stimulators implanted for fecal incontinence were examined prospectively.

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Background: Conventional defecography can reveal abnormalities in patients with evacuatory disorders. With fast dynamic MR imaging systems, MR-defecography has become possible, which does not expose patients to ionizing radiation. The purpose of this study was to assess the correlation of both methods after rectopexy.

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