Publications by authors named "Susanna Porela-Tiihonen"

Article Synopsis
  • **Study Overview**: The APPSYPP trial is a multicenter study investigating the effectiveness of appendectomy versus symptomatic treatment for children aged 7-16 with uncomplicated acute appendicitis confirmed by imaging.
  • **Inclusion Criteria**: Participants must meet specific criteria including imaging-confirmed appendicitis, CRP levels ≤ 65 mg/l, and consent to either surgery or symptomatic management involving an initial hospital stay.
  • **Primary Outcome**: The main goal is to assess treatment success within 30 days, defined by the absence of treatment failure, which varies for both surgical and symptomatic treatments.
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Introduction: Sufentanil is a selective µ-opioid agonist, used intravenously and intrathecally for moderate to severe acute pain. Sublingual sufentanil nanotablets have been developed; 15 mcg tablet for a patient-controlled analgesia device and 30-mcg tablet for a single-dose device administered by a healthcare professional. Dosing interval is a minimum of 20 min for a 15 mcg tablet and a treatment duration of up to 72 hours.

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Sufentanil is a highly selective µ-opioid agonist commonly used by intravenous and intrathecal routes for acute pain. Sublingual sufentanil formulation for patient controlled analgesia (PCA) uses an innovative administration device that suspends a 15 µg nanotablet with a fixed lockout interval. The system is a non-invasive, less burdensome method of opioid delivery compared to intravenous and intrathecal routes.

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Cataract surgery is the most common ophthalmological surgical procedure, and it is predicted that the number of surgeries will increase significantly in the future. However, little is known about the recovery after surgery. The first aim of this study was to evaluate the prevalence, severity and duration of pain and other ocular discomfort symptoms experienced after cataract surgery.

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Purpose: Disease-specific instruments have shown significant gains in measuring health-related quality of life (HRQoL) in subjects having cataract surgery. However, the usage of generic instruments has resulted in conflicting evidence.

Methods: In this prospective study, we have evaluated the impact of cataract surgery on subjects' HRQoL measured with a 15-dimension generic instrument, the 15D.

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Purpose: To evaluate postoperative pain and early recovery in cataract patients.

Patients And Methods: A total of 201 patients who underwent elective first eye cataract extraction surgery were enrolled, and 196 were included in the final analysis. The study design was a single-center, prospective, follow-up study in a tertiary hospital in eastern Finland.

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Cataract extraction surgery is the most common surgical procedure, but knowledge of postoperative pain related to cataract surgery is sparse. In this systematic review, the incidence, prevalence, and management of pain after phacoemulsification surgery were identified using PubMed and Scopus. Selected studies were restricted to randomized controlled trials with interventions on postoperative inflammation and pain.

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