Investigating Anthrax-Associated Virulence Genes among Archival and Contemporary Group Genomes.

causes anthrax through virulence factors encoded on two plasmids. However, non- organisms within the closely related, environmentally ubiquitous group (BCG) may cause an anthrax-like disease in humans through the partial adoption of anthrax-associated virulence genes, challenging the definition of anthrax disease. To elucidate these phenomena and their evolutionary past, we performed whole-genome sequencing on non- BCG isolates, including 93 archival (1967-2003) and 5 contemporary isolates (2019-2023).

The population genomics of within-host Mycobacterium tuberculosis.

Recent progress in genomic sequencing from patient samples has allowed for the first detailed insight into the within-host genetic diversity of Mycobacterium tuberculosis (M.TB), revealing remarkably low levels of variation. While this has often been attributed to low mutation rates, other factors have been described, including resistance evolution (i.