Publications by authors named "Susanna Gerlach"
Article Synopsis
- Cortical lesions are a significant aspect of multiple sclerosis pathology, influenced by inflammation, with unclear mechanisms behind demyelination and neurodegeneration.
- Our research combined gene expression and neuropathological analysis, revealing that the unique combination of inflammation and neurodegeneration observed in multiple sclerosis is not seen in other chronic inflammatory diseases.
- We identified more than 80% of specific genes linked to T cell inflammation and oxidative damage, confirming that such damage contributes to the injury of oligodendrocytes and neurons in cortical multiple sclerosis lesions.
