Publications by authors named "Susann Leupold"
Conservative treatment of fingertip injuries in children - first experiences with a novel silicone finger cap that enables woundfluid analysis.
GMS Interdiscip Plast Reconstr Surg DGPW
October 2018
Article Synopsis
- Human fingertips can regenerate effectively after amputation when using semiocclusive dressings, with no reported infections despite bacterial presence.
- A novel silicone finger cap was tested on 12 patients, demonstrating successful healing with no complications or nail deformities.
- Both treatment methods showed excellent outcomes in wound healing, suggesting that bacteria alone do not necessarily lead to infections in such injuries.
Article Synopsis
- Fingertip amputation injuries are common and can heal well with conservative treatment, and researchers are exploring the role of bacteria in this healing process.
- A new silicone finger cap has been developed to create a protective, moist environment for fingertip injuries, instead of traditional film dressings that leak and may cause odor.
- This pilot study, which is the first randomized controlled trial comparing these two treatments, aims to gather data on the safety and effectiveness of the silicone finger cap for both children and adults with fingertip injuries.
The properties and structure of tissue can be visualized without labeling or preparation by multiphoton microscopy combining coherent anti-Stokes Raman scattering (CARS), addressing lipid content, second harmonic generation (SHG) showing collagen, and two-photon excited fluorescence (TPEF) of endogenous fluorophores. We compared samples of sclerotic and nonsclerotic human hippocampus to detect pathologic changes in the brain of patients with pharmacoresistant temporomesial epilepsy (n = 15). Multiphoton microscopy of cryosections and bulk tissue revealed hippocampal layering and micromorphologic details in accordance with reference histology: CARS displayed white and gray matter layering and allowed the assessment of axonal myelin.
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