Publications by authors named "Susann Cordes"
La autoantigen suppresses IRES-dependent translation of the hepatitis A virus.
Biochem Biophys Res Commun
April 2008
Article Synopsis
- The human RNA-binding protein La is crucial for poliovirus translation but suppresses translation and replication of hepatitis A virus (HAV).
- La specifically interacts with different regions of the HAV IRES, differing from its role in poliovirus.
- Unlike poliovirus, HAV's proteinase 3C does not cleave La, suggesting distinct mechanisms in how these viruses utilize IRES elements for translation.