Combination of toxicological and epidemiological approaches for estimating the health impact of atmospheric pollutants. A proof of concept for NO.

Background: Regular monitoring of the air pollutant nitrogen dioxide (NO), an indicator for traffic-related emissions, is a priority in urban environments. The health impacts associated with NO exposure are the result of a combination of factors, including concentration, duration of exposure, and interactions with other pollutants. WHO has established air quality guidelines based on epidemiological studies.