Publications by authors named "Susana Holgado Perez"
Article Synopsis
- The study analyzed the retention rates and predictors of response to biologic disease-modifying anti-rheumatic drugs (bDMARDs) and apremilast in patients with psoriatic arthritis (PsA) over an 18-year period.
- A total of 159 patients received various treatments, with a high discontinuation rate of 60%, primarily due to secondary failure (37%).
- Key predictors for lack of response included male sex, number of swollen joints, and depression, with the best retention observed for anti-TNF agents like infliximab and etanercept.
MASEI is the main validated ultrasound score for the evaluation of enthesis. The lack of studies facing the agreement to achieve for the interpretation of the MAdrid Sonographic Enthesis Index (MASEI) among researchers from different centers in multicenter studies is of concern. The aim of this multicenter was to evaluate the interobserver reliability of MASEI.
View Article and Find Full Text PDFHearing in Paget's disease of bone.
Acta Otorrinolaringol Esp (Engl Ed)
November 2019
Introduction And Objectives: Paget's disease of bone (PDB) may lead to hearing loss. The present study was conducted with the aim of measuring, characterizing and determining the risk factors for hearing loss in a group of subjects with PDB.
Methods: An observational, transversal, case-control study was conducted, a cohort of 76 subjects diagnosed with PDB in the case group and a control group of 134 subjects were included.
Septic pyogenic arthritis of the acromioclavicular joint is a rare entity that occurs in immunosuppressed patients or those with discontinuity of defense barriers. There are only 15 cases described in the literature. The diagnosis is based on clinical features and the isolation of a microorganism in synovial fluid or blood cultures.
View Article and Find Full Text PDFBackground: The purpose of this study was to assess the cost-effectiveness of bazedoxifene and raloxifene for prevention of vertebral and nonvertebral fractures among postmenopausal Spanish women aged 55-82 years with established osteoporosis and a high fracture risk.
Methods: A Markov model was developed to represent the transition of a cohort of postmenopausal osteoporotic women through different health states, ie, patients free of fractures, patients with vertebral or nonvertebral fractures, and patients recovered from a fracture. Efficacy data for bazedoxifene were obtained from the Osteoporosis Study.
Objective: Due to increasing improvement in the diagnosis, evaluation and management of osteoporosis and the development of new tools and drugs, the Spanish Society of Rheumatology (SER) has promoted the development of recommendations based on the best evidence available. These recommendations should be a reference to rheumatologists and other health professionals involved in the treatment of patients with osteoporosis.
Methods: Recommendations were developed following a nominal group methodology and based on a systematic review.
Introduction: Churg-Strauss Síndrome (SCS) is a necrotizing vasculitis affecting small to medium-sized vessels, characterized by lung involvement, asthma and peripheral blood eosinophilia, and pathologically by the presence of granulomas and eosinophilic infiltrates.
Objectives: This report analizes the characteristics of 9 patients with SCS diagnosed in an university referral center.
Patients And Methods: Retrospective study.
Sarcoidosis may occur in association with lymphoma (sarcoidosis-lymphoma syndrome), it is an uncommon but well-known association. Some clinical features can be similar and clinicians have the challenge to differentiate between these two diseases or prove their co-existence. Clinical and laboratory data are not characteristic in any of them, and an anatomopathological study of lymphadenopathy is necessary to establish the diagnosis.
View Article and Find Full Text PDFObjective: Polyarticular septic arthritis accounts for 15% of all septic arthritis, but there are few references in the literature. We describe characteristics of patients with polyarticular septic arthritis in a rheumatology service.
Patients And Method: Retrospective analysis of patients with septic arthritis involving more than one joint.
Background And Objective: We intended to describe the clinical characteristics, treatment and evolution of 26 patients with adult onset Still's disease.
Patients And Method: This was a retrospective study (1984-2004). The clinical records of patients with adult onset Still's disease were reviewed.