Publications by authors named "Susana Bustos-Rodriguez"

Article Synopsis
  • Researchers need nanocrystals with specific shapes for better catalysts, but traditional methods don’t allow for shape control.
  • This study successfully synthesized concave platinum nanocubes with {110} facets and showed how they grow on a Pt(111) support, creating detailed nanostructured surfaces.
  • By carefully selecting the support's crystallographic orientation, scientists can selectively immobilize desired nanostructures from a mixed solution, leading to new possibilities in nanocrystal development.
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Oxidative stress is considered as an important factor and an early event in the etiology of Alzheimer's disease (AD). Cu bound to the peptide amyloid-β (Aβ) is found in AD brains, and Cu-Aβ could contribute to this oxidative stress, as it is able to produce in vitro H2O2 and HO˙ in the presence of oxygen and biological reducing agents such as ascorbate. The mechanism of Cu-Aβ-catalyzed H2O2 production is however not known, although it was proposed that H2O2 is directly formed from O2 via a 2-electron process.

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Evaluation of Zn affinity for the amyloid-β peptide involved in Alzheimer's disease and its modified counterparts is reported. This was made possible by the use of a new water-soluble chelator, the properties of which have also been described. Changes in the peptide sequence that impact Zn affinity are briefly discussed.

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