Publications by authors named "Susana Boavida"
Extra-cavitary primary effusion lymphoma (PEL), often associated with human herpes virus 8 (HHV8) infection, represents a rare and aggressive form of non-Hodgkin lymphoma, which is predominantly found in individuals with severe immunosuppression. As an acquired immunodeficiency syndrome (AIDS)-associated lymphoma, PEL typically manifests in the context of advanced human immunodeficiency virus (HIV) infection, requiring tailored therapeutic approaches to manage both the lymphoma and underlying immunodeficiency. A 53-year-old male patient from Cape Verde presented with a three-day history of fever, night sweats, right iliac fossa pain, hematochezia, and an unintentional weight loss of five kilograms over the previous two months.
View Article and Find Full Text PDFCryptococcal meningitis is a common opportunistic infection in HIV-infected patients and other immunocompromised people. Pregnancy, which is a state of relative immunosuppression, can also be a risk factor for the development of cryptococcal meningitis. We report a clinical case of a 41-year-old woman who developed a severe meningeal syndrome after an otherwise normal pregnancy.
View Article and Find Full Text PDFArticle Synopsis
- CD4(+) regulatory T cells (Tregs) help maintain immune balance by regulating T cell activation, which is crucial for preventing autoimmune responses.
- Research on 53 HIV-infected patients undergoing highly active antiretroviral therapy (HAART) showed that those with low CD4(+) T cell counts (Nadir <200 cells/µL) and high Tregs percentages had poorer immune recovery.
- The study indicates that a high frequency of Tregs can negatively impact CD4(+) T cell recovery, particularly in individuals who don’t respond well to treatment, suggesting that monitoring Tregs levels could be important for optimizing HAART strategies.