Characteristics and practicalities of a new basal insulin.

Although current basal insulin analogues offer substantial improvements over previous therapies, they are not yet ideal. Issues such as fear of hypoglycaemia and the complexity and rigidity of dosing regimens are significant barriers to the initiation and intensification of insulin therapy. Fear of hypoglycaemia in particular has been proven to affect negatively adherence and health-related quality of life for people with diabetes.