External skeletal fixation of fractures in cattle.

External skeletal fixation (ESF) is a versatile method for rigid immobilization of long bone fractures in cattle. Traditional ESF devices may be used in young calves for clinical management of open fractures. Transfixation pinning and casting is an adaptation of ESF principles to improve versatility and clinical management of selected fractures.

Duodenal obstruction caused by duodenal sigmoid flexure volvulus in dairy cattle: 29 cases (2006-2010).

Objective: To characterize duodenal sigmoid flexure volvulus (DSFV) and determine the prognosis for affected cattle undergoing surgery.

Design: Retrospective case series.

Animals: 29 dairy cattle.

Acute compartment syndrome in the pelvic limb of a cow following biopsy of a skeletal muscle-associated hemangiosarcoma.

Case Description: A 6-year-old Holstein cow was examined because of chronic lameness and swelling near the stifle joint of the left pelvic limb.

Clinical Findings: A mass was palpated in the soft tissues lateral to the proximal aspect of the left tibia. Multiple attempts to obtain a biopsy specimen of the mass resulted in acute compartment syndrome of the femoral compartment (tensor fasciae latae and biceps femoris muscles) and lateral tibial compartment (cranial tibial and peroneus tertius muscles) with associated sciatic nerve paralysis.

Congenital enlargement of the suburethral diverticulum in a Holstein calf.

A 3-month-old, female Holstein calf was examined because of marked perineal swelling and tenesmus of 4-days duration. A congenitally enlarged urethral diverticulum was diagnosed using fluoroscopic and ultrasonographic imaging techniques. The urethral diverticulum was surgically resected and the perineal area was reconstructed.

Repair of transverse process fractures of multiple lumbar vertebrae in an adult dairy cow.

Objective: To report lumbar vertebrae transverse process fracture repair using a narrow 3.5 mm limited contact dynamic compression plate (LC-DCP) in an adult dairy cow.

Study Design: Case report.

Unilateral nephrectomy in 10 cattle.

Objective: To describe clinical and imaging findings, treatment, and long-term outcome of cattle undergoing unilateral nephrectomy.

Study Design: Case series.

Animals: Cattle (n=10).

Seminal vesiculitis.

Although accurate diagnosis of seminal vesiculitis still seems to be a problem, the disease can be treated surgically if the value of the animal warrants. Although this technique offers superior surgical exposure and seems to be successful in young bulls, its value in adult bulls is still questionable. There have been no reports of successful seminal vesiculectomy in aged bulls of which the authors are aware.

Synthesis and biological evaluation of inhibitors of thymidine monophosphate kinase from Bacillus anthracis.

Nineteen lipophilic thymidine phosphate-mimicking compounds were designed and synthesized as potential inhibitors of thymidine monophosphate kinase of Bacillus anthracis, a Gram-positive bacterium that causes anthrax. These thymidine analogues were substituted at the 5'-postion with sulfonamide-, amide-, (thio)urea-, or triazole groups, which served as lipophilic surrogates for phosphate. Three of the tested compounds produced inhibition of B.

Evaluation of Bacillus anthracis thymidine kinase as a potential target for the development of antibacterial nucleoside analogs.

Bacillus anthracis, which causes anthrax, has attracted attention because of its potential use as a biological weapon. The risk of multidrug resistance against B. anthracis increases the need for antibiotics with new molecular targets.