Publications by authors named "Susan M Burge"
Pediatric pyoderma gangrenosum with splenic and pulmonary involvement.
Pediatr Dermatol
February 2014
An 8-year-old boy presented with ulcers on the lip and limbs, scattered pustules, fever, and general malaise. Further investigation revealed splenic and pulmonary lesions. A diagnosis of pyoderma gangrenosum with splenic and pulmonary involvement was made.
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- Darier disease (DD) is a rare skin disorder inherited in an autosomal dominant manner, linked to mutations in the ATP2A2 gene, which is involved in both skin and brain function.
- Researchers screened 95 unrelated DD patients, discovering 66 potentially pathogenic mutations, out of which 45 are considered novel.
- The findings indicate a diverse range of mutations in ATP2A2, suggesting they may not be limited to specific families, which enhances our understanding of how DD develops.
Article Synopsis
- The study aimed to evaluate how different teaching methods affect UK medical students' confidence in dermatology, an important aspect of their education given the high prevalence of skin conditions.
- Results from a survey of 449 final-year students indicated that teaching from dermatology specialists and small-group, clinical learning experiences significantly boosted students' confidence, especially in handling chronic conditions over emergencies.
- Despite these positive influences, a notable percentage of students still felt inadequately prepared to assess and manage skin conditions, highlighting a need for improved dermatology training in medical curricula.
Leg ulcers are a common health problem. Ulcers of any etiology including venous ulcers may be very painful, but until recently, health professionals have not been good at recognizing or managing this type of pain. It is important to clarify the type, severity, and frequency of pain and to anticipate pain at dressing changes.
View Article and Find Full Text PDFATP2C1, encoding the human secretory pathway Ca(2+)-ATPase (hSPCA1), was recently identified as the defective gene in Hailey-Hailey disease (HHD), an autosomal dominant skin disorder characterized by abnormal keratinocyte adhesion in the suprabasal layers of the epidermis. In this study, we used denaturing high-performance liquid chromatography to screen all 28 exons and flanking intron boundaries of ATP2C1 for mutations in 9 HHD patients. Nine different mutations were identified.
View Article and Find Full Text PDFUndergraduate medical curricula: are students being trained to meet future service needs?
Clin Med (Lond)
October 2003
The General Medical Council's recommendations for medical education in Tomorrow's doctors led to a major review of undergraduate medical curricula. The changes have affected all those who teach medical students. This article discusses the background to the GMC's recommendations to define core curricula but provide choice, including options in the humanities, to 'integrate' courses and to introduce new methods of teaching and learning.
View Article and Find Full Text PDFDarier's disease is a rare cutaneous disease with an autosomal dominant mode of inheritance. Greasy papules and plaques arise on the seborrheic areas and in the flexures and almost all patients have nail abnormalities. Acantholysis and dyskeratosis are the typical histological findings.
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