Publications by authors named "Susan L Fong"
Background: At least 30% of youth with epilepsy will require transition from pediatric to adult neurology care. Many adolescents and young adults (AYAs) with epilepsy are inadequately prepared for health care transition, which may contribute to health care disruptions and decreased quality of life. The current study aimed to add to the growing body of literature on health care transition in epilepsy by characterizing a sample of AYAs with epilepsy and assessing the relationship between pre-existing and behaviorally modifiable factors and epilepsy-specific transition readiness.
View Article and Find Full Text PDFObjective: We investigated the role of transverse temporal gyrus and adjacent cortex (TTG+) in facial expressions and perioral movements.
Methods: In 31 patients undergoing stereo-electroencephalography monitoring, we describe behavioral responses elicited by electrical stimulation within the TTG+. Task-induced high-gamma modulation (HGM), auditory evoked responses, and resting-state connectivity were used to investigate the cortical sites having different types of responses on electrical stimulation.
Article Synopsis
- * A study reviewed data from six pediatric epilepsy centers and found that 14% of 259 patients were treated with felbamate, showing a 62% effectiveness in reducing seizures.
- * Felbamate was more effective than other common medications like levetiracetam (15%) and valproic acid (32%), and its efficacy was comparable to the ketogenic diet (69%), suggesting it should be considered as a key treatment option for EMAtS.
Article Synopsis
- The study analyzed the safety of intravenous lacosamide (LCM) in treating seizures in 686 children and 28 neonates over more than a decade.
- Adverse events linked to LCM were rare, occurring in only 1.5% of children, while no adverse events were reported in neonates, indicating a high safety profile.
- However, children receiving a higher-than-recommended initial dose faced a doubled risk of developing a rash, underlining the importance of adhering to dosage guidelines.
Article Synopsis
- The study compares the effectiveness and safety of electrical stimulation mapping (ESM) using subdural electrodes (SDE) and stereoelectroencephalography (SEEG) in functional brain localization for patients with epilepsy.
- Results showed similar language and motor responses between the two methods, but SEEG had a higher incidence of sensory responses and less frequent afterdischarges (ADs) and EISs (unwanted seizures).
- Overall, SEEG is considered a safer and more effective option for functional brain mapping due to its favorable thresholds and capacity for identifying sensory areas compared to SDE.
Objective: To clinically validate the connectivity-based magnetoencephalography (MEG) analyses to identify seizure onset zone (SOZ) with comparing to equivalent current dipole (ECD).
Methods: The ECD cluster was quantitatively analyzed by calculating the centroid of the cluster and maximum distance (the largest distance between all dipoles). The "primary hub" was determined by the highest eigencentrality.
Cornelia de Lange syndrome is a rare developmental malformation syndrome characterized by small stature, limb anomalies, distinctive facial features, developmental delays, and behavioral issues. The diagnosis of Cornelia de Lange syndrome is made clinically or on the basis of an identified variant in one of the genes associated with Cornelia de Lange syndrome. variants are the cause of 5% of the cases of Cornelia de Lange syndrome.
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