Publications by authors named "Susan Kerkoutian"
Article Synopsis
- ProEx C is an antibody cocktail used to identify specific proteins involved in cell division, primarily aiding in the diagnosis of dysplasia in gynecological specimens.
- A study evaluated its effectiveness in distinguishing between different grades of urothelial lesions, classifying 64 patient specimens into various groups based on their cancer status.
- Results showed ProEx C had high sensitivity (95%) and specificity (95%) for detecting urothelial carcinoma, proving effective in differentiating between benign and malignant lesions, and is the first publication to document its use in this context.
Article Synopsis
- Pomegranates have been shown to slow prostate cancer growth and affect PSA doubling times in human studies, but their effects on prostate tissue need more research.
- A study involving 70 men tested pomegranate extract (POMx) against a placebo, focusing on reducing oxidative stress biomarker 8-OHdG in prostate tissue.
- Although POMx did not significantly reduce 8-OHdG levels, it was well tolerated and led to detectable pomegranate metabolites in prostate tissues, indicating a need for larger, longer studies to explore its potential benefits fully.
The 2008 edition of the WHO Classification of Tumours of Haematopoietic and Lymphoid tissues recognizes a new diagnostic entity termed "other iatrogenic immunodeficiency-associated lymphoproliferative disorders" highlighting lymphomas arising in patients treated with immunosuppressive agents for autoimmune disorders. The role of antitumor necrosis factor alpha therapy (anti-TNFα) and lymphoma risk in rheumatoid arthritis (RA) patients remains unclear; therefore, the goal of our study was to determine whether anti-TNFα therapy is associated with iatrogenic lymphomas. A meta-analysis of all randomized controlled clinical trials published (2000-2009) in RA patients receiving anti-TNFα therapy was performed.
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