Thrombocytosis during antifungal therapy of candidemia.

Background: Secondary, "reactive," thrombocytosis has been attributed to bacterial infection and treatment with multiple pharmaceuticals and may be associated with an increase in the incidence of gastrointestinal tract bleeding and thrombotic events (eg, stroke).

Objective: To characterize the dynamics of thrombocytosis in patients with candidemia receiving antifungal therapy.

Methods: We initiated a retrospective observational description of patients with candidemia who were treated with antifungal agents.