Resistance to oral vitamin K for reversal of overanticoagulation during Crohn's disease relapse.

Objective: The purpose of this case report is to describe oral vitamin K resistance in a patient with concomitant Crohn's disease (CD) relapse and supratherapeutic anticoagulation. Additionally, a literature review was conducted to explore the mechanism and supporting evidence for poor response to oral vitamin K during CD relapse.

Case Report: A 36 year-old female presented with an elevated International Normalized Ratio (INR) of 7.