A Psychiatric Nurse's Perspective: Helping Patients Undergo Repetitive Transcranial Magnetic Stimulation (rTMS) for Depression.

With the October 2008 Food and Drug Administration approval of repetitive transcranial magnetic stimulation (rTMS) for depression treatment, the establishment and administration of rTMS clinical treatment programs are critically important and emerging areas for psychiatric nursing leadership. There is growing recognition that many patients are unable to tolerate antidepressant medications and require alternative antidepressant treatment approaches. The enormous growth in the field of brain stimulation creates exciting new therapeutic options for patients with treatment-resistant depression.

Hypoxia has a greater effect than exercise on the redistribution of pulmonary blood flow in swine.

Strenuous exercise combined with hypoxia is implicated in the development of high-altitude pulmonary edema (HAPE), which is believed to result from rupture of pulmonary capillaries secondary to high vascular pressures. The relative importance of hypoxia and exercise in altering the distribution of pulmonary blood flow (PBF) is unknown. Six chronically catheterized specific pathogen-free Yorkshire hybrid pigs (25.

Quantifying the genetic influence on mammalian vascular tree structure.

The ubiquity of fractal vascular trees throughout the plant and animal kingdoms is postulated to be due to evolutionary advantages conferred through efficient distribution of nutrients to multicellular organisms. The implicit, and untested, assertion in this theory is that the geometry of vascular trees is heritable. Because vascular trees are constructed through the iterative use of signaling pathways modified by local factors at each step of the branching process, we sought to investigate how genetic and nongenetic influences are balanced to create vascular trees and the regional distribution of nutrients through them.

Qualitative assessment of risk for monkeypox associated with domestic trade in certain animal species, United States.

In 2003, US officials identified several human monkeypox cases and traced the virus exposure to infected captive prairie dogs. The virus was likely introduced through a shipment of imported African rodents, which were kept with other mammals, including prairie dogs, in a pet distribution facility in the Midwest. To prevent the further introduction and spread of the virus, federal agencies restricted the importation of African rodents and restricted the domestic trade or movement of prairie dogs and certain other rodents.

The spatial-temporal redistribution of pulmonary blood flow with postnatal growth.

The pulmonary vascular tree undergoes remarkable postnatal development and remodeling. While a number of studies have characterized longitudinal changes in vascular function with growth, none have explored regional patterns of vascular remodeling. We therefore studied six neonatal pigs to see how regional blood flow changes with growth.

Structure and size of bronchopulmonary anastomoses in sheep lung.

The distribution and drainage of bronchial arterial blood flow are complex. We used two different methods to study the bronchial-pulmonary anastomoses in sheep lung. Initially, we injected two different sizes of fluorescent microspheres (15 and 100 microm diameter) into the bronchial artery and histologically determined where the different-size microspheres were entrapped in the lung.

Intravital microscopic observations of 15-microm microspheres lodging in the pulmonary microcirculation.

Vascular infusions of 15-microm-diameter microspheres are used to study pulmonary blood flow distribution. The sites of microsphere lodging and their effects on microvascular perfusion are debated but unknown. Using intravital microscopy of the subpleural surface of rat lungs, we directly observed deposition of fluorescent microspheres.

Municipal heat wave response plans.

Approximately 400 people die from extreme heat each year in the United States, and the risk of heat waves may increase as a result of global climate change. Despite the risk of heat-related morbidity and mortality, many cities lack written heat response plans. In a review of plans from 18 cities at risk for heat-related mortality, we found that many cities had inadequate or no heat response plans.

Soluble gas exchange in the pulmonary airways of sheep.

We studied the airway gas exchange properties of five inert gases with different blood solubilities in the lungs of anesthetized sheep. Animals were ventilated through a bifurcated endobronchial tube to allow independent ventilation and collection of exhaled gases from each lung. An aortic pouch at the origin of the bronchial artery was created to control perfusion and enable infusion of a solution of inert gases into the bronchial circulation.

Validation of the Nonin 8600V Pulse Oximeter for heart rate and oxygen saturation measurements in rats.

This report validates the use and limitations of the Nonin Pulse Oximeter for measuring heart rate and oxygen saturation in rats. Eight anesthetized Sprague-Dawley rats were intubated and catheterized. Oxygen saturation was directly measured from arterial blood by using a Radiometer OSM3 Hemoximeter adjusted for rat blood as well as indirectly by using the Nonin Pulse Oximeter.

Prevalence of blood lead levels >or= 5 micro g/dL among US children 1 to 5 years of age and socioeconomic and demographic factors associated with blood of lead levels 5 to 10 micro g/dL, Third National Health and Nutrition Examination Survey, 1988-1994.

Objectives: As part of an investigation into the impact of a potential revision in federal childhood lead poisoning prevention policy that would result in screening children for blood lead levels (BLLs) >or=5 micro g/dL rather than the current 10 micro g/dL, we analyzed the most recent available, nationally representative data to identify prevalence of BLLs >or=5 micro g/dL and socioeconomic and demographic characteristics of 1- to 5-year-old children with BLLs >or=5 but <10 micro g/dL.

Methods: We performed statistical analyses on data from the Third National Health and Nutrition Examination Survey (NHANES III) (1988-1994) to describe trends in BLLs >or=5 micro g/dL overall and among subpopulations of children <6 years old and to compare risk factors for falling within 1 of 3 groups of children (those with BLLs >or=5 but <10 micro g/dL; >or=10 but <20 micro g/dL; and >or=20 micro g/dL) using the group reported as 0.7 to <5 micro g/dL as the referent.

Should the Centers for Disease Control and Prevention's childhood lead poisoning intervention level be lowered?

The US Centers for Disease Control and Prevention (CDC) in 1991 chose 10 micro g/dL as an initial screening level for lead in children's blood. Current data on health risks and intervention options do not support generally lowering that level, but federal lead poisoning prevention efforts can be improved by revising the follow-up testing schedule for infants aged 1 year or less with blood lead levels of 5 micro g/dL or higher; universal education about lead exposure risks; universal administration of improved, locally validated risk-screening questionnaires; enhanced compliance with targeted screening recommendations and federal health program requirements; and development by regulatory agencies of primary prevention criteria that do not use the CDC's intervention level as a target "safe" lead exposure.

Axial and radial distribution of the bronchial vasculature in sheep.

A morphometric analysis was made on the bronchial vasculature of intrapulmonary airways in sheep lungs. This study provides the parameters to calculate the quantity of soluble gas diffusion between the vasculature and airways for use in a mathematical model describing heat and mass exchange in the lungs. To achieve these results, the lungs of four adult sheep (30-36 kg.