This article summarizes the proceedings of a symposium presented at the 2005 Research Society on Alcoholism meeting in Santa Barbara, California. This symposium begins with a description by Michael Windle of structural equation modeling (SEM), including the assets and liabilities of this approach. Next, Marc Schuckit and Tom Smith demonstrate the application of an SEM approach to understanding the impact of a low level of response to alcohol, using data from both adolescent and adult populations.
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