Efficacy and acceptability of varenicline for alcoholism: A systematic review and meta-analysis of randomized-controlled trials.

Background: Current pharmacological treatment for alcoholism remains unsatisfactory. While there have been several clinical trials investigating the efficacy and safety of the therapeutic use of varenicline in alcoholism, no definitive review of this topic has been carried out. This systematic review aimed to determine the efficacy and acceptability of the use of varenicline in treating alcoholism.