Publications by authors named "Sureshkumar B Choudhary"
Purpose: Dynamic in-situ proton (H) magnetic resonance imaging (MRI) and H T-relaxometry experiments are described in an attempt to: (i) understand the physical processes, that occur during the reconstitution of lyophilized bovine serum albumin (BSA) and monoclonal antibody (mAb) proteins; and (ii) objectify the reconstitution time.
Methods: Rapid two-dimensional H MRI and diffusion weighted MRI were used to study the temporal changes in solids dissolution and characterise water mass transport characteristics. One-shot T relaxation time measurements were also acquired in an attempt to quantify the reconstitution time.