Synthesis, supramolecular organization and thermotropic phase behaviour of -acyltris(hydroxymethyl)aminomethane.

Herein, we reported the supramolecular organization of -acyltris(hydroxymethyl)aminomethane (NATM) in the solid state as well as in aqueous solution. Single crystal X-ray diffraction revealed that NATM adopts a fully interdigitized structure. The thermodynamic parameters associated with thermotropic phase behaviour of NATM was determined by differential scanning calorimetry.