Unveiling the potential of Hamigeran-B from marine sponges as a probable inhibitor of Nipah virus RDRP through molecular modelling and dynamics simulation studies.

The Nipah virus (NiV) is an emerging pathogenic paramyxovirus that causes severe viral infection with a high mortality rate. This study aimed to model the effectual binding of marine sponge-derived natural compounds (MSdNCs) towards RNA-directed RNA polymerase (RdRp) of NiV. Based on the functional relevance, RdRp of NiV was selected as the prospective molecular target and 3D-structure, not available in its native form, was modelled.

Long-term response of dragon fruit () to transformed rooting zone of a shallow soil improving yield, storage quality and profitability in a drought prone semi-arid agro-ecosystem.

Agricultural crops especially fruit trees are constrained by edaphic stresses in shallow soils with low water retention and poor fertility. Therefore, interventions of shifting to trench planting for better root anchorage and replacing the filling soil were evaluated for 8 years in dragon fruit () cultivated in Deccan Plateau of peninsular India. When averaged for last 5-years, 44 % higher fruit yield (18.

Morvan's syndrome Presenting with Psychiatric Manifestations - A Case Report and Review of the Literature.

The term "la chorιe fibrillare" was used by the French physician Augustine Marie Morvan to describe a syndrome showing hyperactivity features involving the central, autonomic, and peripheral nervous system. The central hyperactivity symptoms are confusion, behavioral problems, hallucinations, myoclonus, and insomnia; the autonomic hyperactivity symptoms are hyperhidrosis and variations in blood pressure; and peripheral hyperexcitability is characterized by painful cramps, myokymia, and neuromyotonia. Here, we present a case that has typical features of Morvan's syndrome and provides a brief description based on available literature.

Fabrication of Zwitterion TiO Nanomaterial-Based Nanocomposite Membranes for Improved Antifouling and Antibacterial Properties and Hemocompatibility and Reduced Cytotoxicity.

Although zwitterion nanomaterials exhibit outstanding antifouling property, hemocompatibility, and antibacterial activity, their poor solubility in organic solvents limits their practical applications. In the present study, natural lysine (amino acids) was surface-grafted onto one-dimensional (1D) TiO nanofibers (NFs) through an epoxy ring opening in which the 3-glycidyloxypropyl (dimethoxy) methyl silane was used as a coupling agent. Chemical binding and morphological studies, such as Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and transmission electron microscopy, were conducted to confirm the successful grafting of lysine onto the TiO NFs.

Swift production of rhamnolipid biosurfactant, biopolymer and synthesis of biosurfactant-wrapped silver nanoparticles and its enhanced oil recovery.

Microbial enhanced oil recovery (MEOR) is a kind of enhanced oil recovery (EOR) development, often used as a tertiary stage where oil recovery is no longer possible utilizing primary and secondary conventional techniques. Among a few potential natural operators valuable for MEOR, biosurfactants, biopolymers and biosurfactant based nanoparticles assume key jobs. Biosurfactant which are produced by microorganisms' act as are surface active agents that can be used as an alternative to chemically synthesized surfactants.

Long-term effectiveness and safety of image-based, transperineal combined intracavitary and interstitial brachytherapy in treatment of locally advanced cervical cancer.

Purpose: The aim of the study was to evaluate the impact of image-based combined intracavitary-interstitial brachytherapy (IC-ISBT) using a transperineal template in locally advanced cervical cancer treatment.

Methods And Materials: A total of 94 patients of cervical cancer stage IIB-IVA underwent image-based transperineal interstitial brachytherapy without tandem (ISBT) or with tandem (IC-ISBT) between June 2008 and June 2018 at our institution. After pelvic chemoradiation, 42 patients underwent ISBT and 52 IC-ISBT.

Facile synthesis of gold nanoparticles using carbon dots for electrochemical detection of neurotransmitter, dopamine in human serum and as a chemocatalyst for nitroaromatic reduction.

Herein, the authors reported a carbon dots mediated synthesis of gold nanoparticles (AuNPs) at room temperature. Transmission electron microscopy revealed that the AuNPs are spherical in shape with a size of 10 nm. As-prepared AuNPs was immobilised on carbon paste electrode and subjected to electrochemical sensing of an important neurotransmitter dopamine.

Understanding and improving the reusability of phosphate adsorbents for wastewater effluent polishing.

Phosphate is a vital nutrient for life but its discharge from wastewater effluents can lead to eutrophication. Adsorption can be used as effluent polishing step to reduce phosphate to very low concentrations. Adsorbent reusability is an important parameter to make the adsorption process economically feasible.

Biogenic iron oxides for phosphate removal.

Biogenic iron oxides (BioFeO) formed by sp. and sp. were compared with chemically formed iron oxides (ChFeO) for their suitability to remove and recover phosphate from solutions.

Disulphide linkage: To get cleaved or not? Bulk and nano copper based SERS of cystine.

Different nano-structures of noble metals have been the conventional substrates for carrying out Surface Enhanced Raman Spectroscopy (SERS). In this paper we examine electrodeposited copper (Cu) nano-structures on pencil graphite as novel substrate to carry out SERS measurements by considering l-cystine (Cys-Cys) (dimer of the amino acid cysteine) as the probe. The formation of monolayer of the probe molecule on the substrates was confirmed using cyclic voltammetric measurements.

Correction: The photocatalytic role of electrodeposited copper on pencil graphite.

Correction for 'The photocatalytic role of electrodeposited copper on pencil graphite' by Arathi P. J. et al.

Structural insights on bioremediation of polycyclic aromatic hydrocarbons using microalgae: a modelling-based computational study.

Research on bioremediation of polycyclic aromatic hydrocarbons (PAHs) has established that several remediating microbial species are capable of degrading only low molecular weight (LMW)-PAHs, whereas high molecular weight (HMW)-PAHs are hardly degradable. In the present study, the efficiency of degradation of both LMW and HMW-PAHs by cytochrome P450 monooxygenase (CYP) of microalgae was studied. CYP have a key role in the detoxification of xenobiotics.

The photocatalytic role of electrodeposited copper on pencil graphite.

We report on the ability of template-electrodeposited copper on pencil graphite as a novel and cost effective photocatalyst by considering the photodimerization of p-aminothiophenol (p-ATP) to 4,4'-dimercaptoazobenzene.

Olanzapine has better efficacy compared to risperidone for treatment of negative symptoms in schizophrenia.

Objective: The safety and efficacy profile of risperidone and olanzapine were compared in a double-blind trial that used doses widely accepted in clinical practice.

Methods: Subjects ( = 71) who met Diagnostic and Statistical Manual of Mental Disorders-IV criteria for schizophrenia were randomly assigned to receive 2-8 mg/day of risperidone (mean modal dose = 5.5 mg/day) or 5-20 mg/day of olanzapine (mean modal dose = 14.

A study on the glycemic, lipid and blood pressure control of type 2 diabetes patients of Kerala.

Aim: Aim of the study was to detect the level of comprehensive diabetes control among the diabetic patients of Kerala, India.

Method: Patients (1200) were randomly selected from a diabetes care center. Their blood sugar and other biochemical and anthropometric measurements were done and statistically analyzed.

Phytoproteins in green leaves as building blocks for photosynthesis of gold nanoparticles: An efficient electrocatalyst towards the oxidation of ascorbic acid and the reduction of hydrogen peroxide.

Herein, we present a simple and green method for the synthesis of gold nanoparticles (AuNPs) using the phytoproteins of spinach leaves. Under ambient sunlight irradiation, the isolated phytoprotein complex from spinach leaves reduces the gold chloride aqueous solution and stabilizes the formed AuNPs. As prepared nanoparticles were characterized by UV-visible spectroscopy, Fourier transform infra-red (FTIR) spectroscopy, zeta potential, transmission electron microscopy (TEM) and energy dispersive X-ray analysis (EDS).

Arsenic adsorption by iron-aluminium hydroxide coated onto macroporous supports: Insights from X-ray absorption spectroscopy and comparison with granular ferric hydroxides.

This paper evaluates the arsenic adsorption characteristics of a macroporous polymer coated with coprecipitated iron-aluminium hydroxides (MHCMP). The MHCMP adsorbent-composite fits best with a pseudo-second order model for As(III) and a pseudo-first order kinetic model for As(V). The MHCMP shows a maximum adsorption capacity of 82.

Effect of Agility Exercises on Knee Health Status among Patients with Osteoarthritis.

Osteoarthritis is one of the most common causes of disability due to limitations of joint movement and accounts for more hospitalisations which ultimately result in increased health care costs. The present study was carried out to assess the effect of agility exercises on knee health status among patients with osteoarthritis. It was a quasi experimental study--one group pre-test post-test control group design- conducted over a period of three months in 50 subjects who were diagnosed as having mild and moderate knee osteoarthritis attending outpatient department of physical medicine and rehabilitation, Medical College Hospital, Thiruvananthapuram.

Electrospun nanofibers: a prospective electro-active material for constructing high performance Li-ion batteries.

In the present review, we describe the development of a high energy density LIB fabricated with all 1D nanofibers as the anode and cathode, as well as a separator-cum-electrolyte prepared by an electrospinning technique without compromising the power capability and cycle life. Such a unique assembly certainly enables realizing the advantages of using 1D nanostructures in practical LIBs, irrespective of the anode or cathode in the presence of gelled polyvinylidene fluoride-co-hexafluoropropylene as the separator-cum-electrolyte. Outstanding cycling profiles with high power densities were noted for all the configurations evaluated.

Exceptional performance of TiNb₂O₇ anode in all one-dimensional architecture by electrospinning.

We report the extraordinary performance of an Li-ion battery (full-cell) constructed from one-dimensional nanostructured materials, i.e. nanofibers as cathode, anode, and separator-cum-electrolyte, by scalable electrospinning.