Publications by authors named "Suresh K"

Lack of O and high concentrations of iron (Fe) are common in flooded soils where Rice (Oryza sativa L.) is cultivated. We tested the hypothesis that growing in stagnant or high Fe conditions might induce the formation of apoplastic barriers in roots with different properties and chemical compositions.

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  • Humans and animals are at risk of avian influenza, which could lead to a pandemic from a new virus that spreads effectively between humans.
  • The study conducted a meta-analysis on three microarray datasets to identify gene expression related to avian influenza, discovering 1,284 common differentially expressed genes.
  • Key findings included important biological pathways related to immune response and specific hub genes, which could provide insights for developing better treatments for the disease.
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Angiomyofibroblastoma is a benign, usually small neoplasm typically constituted by spindle-shaped and epithelioid cells in a vascularized, myxoid-fibrous stromal background. It is most often seen in the superficial genitalia of female patients of reproductive age. However, various clinical and histologic features have been reported, including tumors in male patients, malignant transformation, extragenital sites, huge sizes, and a prominent lipomatous pattern.

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Bacillus anthracis, a gram-positive bacillus capable of forming spores, causes anthrax in mammals, including humans, and is recognized as a potential biological weapon agent. The diagnosis of anthrax is challenging due to variable symptoms resulting from exposure and infection severity. Despite the availability of a licensed vaccines, their limited long-term efficacy underscores the inadequacy of current human anthrax vaccines, highlighting the urgent need for next-generation alternatives.

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Understanding the reciprocal interaction between root development and coadapted beneficial microbes in response to elevated CO (eCO) will facilitate the identification of nutrient-efficient cultivars for sustainable agriculture. Here, systematic morphological, anatomical, chemical and gene expression assays performed under low-nitrogen conditions revealed that eCO drove the development of the endodermal barrier with respect to L-/S-shaped lateral roots (LRs) in rice. Next, we applied metabolome and endodermal-cell-specific RNA sequencing and showed that rice adapts to eCO by spatially recruiting diazotrophs via flavonoid secretion in L-shaped LRs.

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Introduction: Pulmonary arterial hypertension (PAH) involves progressive cellular and molecular change within the pulmonary vasculature, leading to increased vascular resistance. Current therapies targeting nitric oxide (NO), endothelin, and prostacyclin pathways yield variable treatment responses. Patients with systemic sclerosis-associated PAH (SSc-PAH) often experience worse outcomes than those with idiopathic PAH (IPAH).

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This paper introduces the design and comprehensive performance evaluation of a novel Multi-Load and Multi-Source DC-DC converter tailored for electric vehicle (EV) power systems. The proposed converter integrates a primary battery power source with a secondary renewable energy source-specifically, solar energy-to enhance overall energy efficiency and reliability in EV applications. Unlike conventional multi-port converters that often suffer from cross-regulation issues and limited scalability, this converter ensures stable power distribution to various EV subsystems, including the motor, air conditioning unit, audio systems, and lighting.

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Peste des petits ruminants (PPR), an acute febrile viral disease impacting goats and sheep flocks, manifests with pyrexia, mucopurulent nasal and ocular discharges, necrotizing and erosive stomatitis, pneumonia, and enteritis. The disease-instigating agent, PPR virus, pertains to the genus in the family. The endemic presence of PPR in India results in notable economic losses due to heightened mortality and morbidity in infected animals.

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Rationale And Objectives: Underrepresentation of minorities is a worsening issue in the field of radiology. Early educational interventions are a promising approach to mitigating this disparity. We present an approach for a radiology department to increase community outreach via establishment of an educational program for local public high school students and building a mentorship pipeline for radiology education.

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Objectives: Radical cystectomy with urinary diversion is the gold standard treatment for bladder cancer (high-risk/muscle invasive). The transperitoneal approach is associated with significant gastrointestinal complications like ileus. In the elderly and frail with a single functional kidney, we describe an extraperitoneal technique of radical cystectomy, with a ureterostomy, to be performed without general anesthesia.

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  • - The study investigates the relationship between proteomic features and outcomes related to right ventricular (RV) health in patients with pulmonary arterial hypertension (PAH), focusing on mortality, RV dilation, and NT-proBNP levels.
  • - A cohort of 117 PAH participants underwent proteomic profiling, revealing significant differences in protein abundance between survivors and nonsurvivors, as well as between patients with dilated and nondilated RVs, with a notable emphasis on extracellular matrix (ECM) proteins.
  • - The findings indicate that specific plasma proteomic profiles correlate with worse clinical outcomes in PAH, suggesting that ECM-related pathways may play a critical role in RV susceptibility to failure, and these results were validated in additional PAH
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  • The study assesses the effectiveness of PLGA-loaded Nedaplatin (PLGA-NDP) in treating oral cancer induced by DMBA in a hamster model, where DMBA exposure led to the development of oral squamous cell carcinoma (OSCC).
  • PLGA-NDP was administered both before and after carcinogen exposure, showing promising results in reducing tumor formation and altering key molecular proteins associated with cancer progression.
  • Findings revealed that PLGA-NDP inhibits Notch signaling, which is linked to apoptosis, suggesting that targeting this pathway could provide a new strategy for treating OSCC.
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  • Anthrax is a zoonotic disease impacting livestock and humans, and the study aimed to identify environmental risk factors to create a better predictive risk map for vaccination.
  • Researchers analyzed anthrax data from 2000-2023 in Karnataka, using machine learning to examine factors like temperature and soil quality to uncover spatial patterns and high-risk areas.
  • The findings identified 11 high-risk districts with a basic reproduction number (Ro) greater than 1.50, suggesting targeted vaccination strategies, with herd immunity thresholds varying from 11.24% to 55.47%.
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This paper introduces a novel design for a universal DC-DC and DC-AC converter tailored for DC/AC microgrid applications using Approximate Dynamic Programming and Artificial Neural Networks (ADP-ANN). The proposed converter is engineered to operate efficiently with both low-power battery and single-phase AC supply, utilizing identical side terminals and switches for both chopper and inverter configurations. This innovation reduces component redundancy and enhances operational versatility.

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  • Rice plants develop an apoplastic barrier in their roots to limit oxygen loss during flooding, which helps maintain root growth in low-oxygen soils.
  • Researchers tested the role of the Leaf Gas Film 1 (LGF1) gene in forming this barrier by comparing a rice mutant lacking LGF1, its wild type, and a variant with increased LGF1 expression.
  • The study found that the mutant had a weaker barrier to oxygen loss, but restoring LGF1 function significantly improved barrier strength, linked to higher glycerol ester levels in root cells.
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Lung endothelium resides at the interface between the circulation and the underlying tissue, where it senses biochemical and mechanical properties of both the blood as it flows through the vascular circuit and the vessel wall. The endothelium performs the bidirectional signaling between the blood and tissue compartments that is necessary to maintain homeostasis while physically separating both, facilitating a tightly regulated exchange of water, solutes, cells, and signals. Disruption in endothelial function contributes to vascular disease, which can manifest in discrete vascular locations along the artery-to-capillary-to-vein axis.

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Pulmonary hypertension (PH) arises from increased pulmonary vascular resistance due to contraction and remodeling of the pulmonary arteries. The structural changes include thickening of the smooth muscle layer from increased proliferation and resistance to apoptosis. The mechanisms underlying apoptosis resistance in PH are not fully understood.

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  • The study examines the elemental composition of the Moon's surface to understand its formation and evolution, utilizing data from multiple lunar missions.
  • Recent in situ measurements from India's Chandrayaan-3 mission reveal that the southern high-latitude regions of the Moon are primarily made up of ferroan anorthosite, indicating a history of crystallization from a lunar magma ocean.
  • The presence of higher magnesium levels compared to calcium suggests that there is mixing with additional mafic materials, while the consistent composition within the surrounding area lends support to remote sensing data accuracy.
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Malignant catarrhal fever (MCF) presents a sporadic yet significant threat to livestock and wildlife. A comprehensive investigation in Karnataka, India into the prevalence and transmission patterns of sheep-associated MCF (SA-MCF) was conducted. A total of 507 sheep peripheral blood leukocyte samples from 13 districts along with 27 cows and 10 buffalo samples from various regions in Karnataka were tested for SA-MCF infection i.

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In root research, hydroponic plant cultivation is commonly used and soil experiments are rare. We investigated the response of 12-day-old barley roots, cultivated in soil-filled rhizotrons, to different soil water potentials (SWP) comparing a modern cultivar (cv. Scarlett) with a wild accession ICB181243 from Pakistan.

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This research paper introduces an avant-garde poly-input DC-DC converter (PIDC) meticulously engineered for cutting-edge energy storage and electric vehicle (EV) applications. The pioneering converter synergizes two primary power sources-solar energy and fuel cells-with an auxiliary backup source, an energy storage device battery (ESDB). The PIDC showcases a remarkable enhancement in conversion efficiency, achieving up to 96% compared to the conventional 85-90% efficiency of traditional converters.

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Background: Children with influenza-like-illness (ILI) often require clinician clearance or antibiotics to return to child care or school. Study objectives were to examine the association between antibiotic receipt during an Emergency Department (ED) visit for ILI and the outcomes of class absenteeism and illness duration.

Methods: A secondary analysis of 251 children aged 2 months to 12 years with uncomplicated ILI discharged from the ED from December 1, 2018 to November 30, 2019 was conducted.

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Background: Precise localized printing of plasmonic nanoparticles at desired locations can find a plethora of applications in diverse areas, including nanophotonics, nanomedicine, and microelectronics. The focused laser beam-assisted optical printing technique has illustrated its potential for the localized printing of differently shaped plasmonic particles. However, the technique is either time-consuming or often requires focused optical radiation, limiting its practical applications.

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Lateral plating alone has been postulated as an alternative for fixation of bicondylar tibial plateau fractures in attempts to limit morbidity associated with dual plating. Characterization of fracture patterns that may facilitate lateral plating alone for bicondylar tibial plateau fractures is not well established. The authors analyzed radiographic and clinical outcomes of isolated lateral plating in patients with at least 6 months of follow-up.

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