Monte Carlo study of dosimetric parameters and dose distribution effect of inhomogeneities and source position of GammaMed Plus source.

Background: The conventional treatment planning system (TPS) gives analytical calculations with approximately ± 15-20% dose uncertainty, which may lead to over exposure of critical organs or under dose of target as well as the presence of inhomogeneities, and the position of source affects the exact dose calculation like in breast and intraluminal brachytherapy.

Aim: To obtain dose distribution parameters of GammaMed Plus high dose rate (HDR) 192 Ir source using Monte Carlo (MC) EGSnrc and GEANT4 codes as well as to find the effect on dose distribution due to source position, and due to presence of air and cortical bone by using MC GEANT4 code, and to find the similarity of both studies with any past study of any HDR brachytherapy source for either as input to TPS or verification of TPS calculations.

Settings And Design: It is done using different software of the computer, e.