Publications by authors named "Surawut Pongsiriwet"
Article Synopsis
- - The study evaluates the effectiveness of toluidine blue (TB)-containing electrospun fibers in detecting oral potentially malignant disorders (OPMDs) with epithelial dysplasia, comparing their performance to traditional histopathological methods.
- - Researchers optimized the concentrations of polyvinylpyrrolidone (PVP) and TB to create fibers and tested them on 36 suspected OPMD lesions, finding that the fibers showed 77.3% sensitivity but only 35.7% specificity in detection.
- - Although the TB-containing fibers demonstrated benefits like easier application and cost-effectiveness for identifying dysplastic changes, their accuracy is not sufficient for standalone diagnosis, suggesting they should be used alongside other diagnostic tools. *
Objective: To develop and validate the Oral Lichen Planus-Disease Activity Scale (OLP-DAS) for assessing overall disease activity of OLP.
Methods: The OLP-DAS was created by refining the Thongprasom criteria, incorporating inputs from the literature and expert review, and integrating pain assessment. Content validity was evaluated in a virtual meeting with 8 Oral Medicine specialists.
Objectives: This study aimed to investigate the expression of programmed death-ligand 1 (PD-L1) and its associations with human papillomavirus (HPV) 16/18 DNA status, p16 expression, demographic, clinicopathologic and risk parameters in patients with oral squamous cell carcinoma (OSCC).
Study Design: A total of 85 formalin-fixed, paraffin-embedded OSCC specimens were collected. HPV16/18 DNA was detected by polymerase chain reaction.
Objectives: The main objectives of this study were to investigate the detection rate of high-risk human papillomavirus types 16 and 18 (high-risk HPV16/18) in oral potentially malignant disorders (OPMDs) including oral leukoplakia (OL) and oral lichen planus (OLP) in a Thai population and their associations with demographic, risk habits, and clinicopathologic features.
Methods: Paraffin-embedded formalin-fixed specimens from 101 OL and 59 OLP patients with patients' demographic, risk habits, and clinicopathologic data were collected. Conventional qualitative polymerase chain reaction was used to detect high-risk HPV16/18 DNA.
Objectives: To identify the prevalence of high-risk human papillomavirus (HPV) genotypes 16 and 18 among patients with oral squamous cell carcinoma (OSCC) in Thailand and investigate the associations of p16 expression and HPV16/18 with the demographic, clinicopathologic, and risk parameters.
Materials And Methods: A total of 403 formalin-fixed paraffin-embedded OSCC specimens from four centers in four regions were obtained. p16 expression was evaluated by immunohistochemistry.
Trigeminal neuralgia (TN) is the neuropathic pain. Mitochondrial dysfunction, increased oxidative stress, and inflammation demonstrated in chronic pain. Carbamazepine (CBZ) is the first-line drug for TN, however, it is still insufficient.
View Article and Find Full Text PDFAim: The aim of the present study was to investigate the prevalence of hepatitis C virus (HCV) infection and evaluate liver enzyme levels in patients from upper northern Thailand with oral lichen planus (OLP).
Methods: A case-control study of 101 patients with OLP and 101 patients without OLP was conducted. Peripheral blood was taken from each patient and screened for anti-HCV antibody using immunochromatography.
Background: High-risk human papillomaviruses (HR-HPV), particularly types 16 and 18, have been found to play an important role in head and neck cancer, including oropharyngeal squamous cell carcinoma (OPSCC) and oral squamous cell carcinoma (OSCC). p16, a cell cycle inhibitor, has been postulated as a surrogate marker for HR-HPV, since p16 is aberrantly overexpressed in such lesions, especially in HR-HPV-positive OPSCC. However, p16 as a surrogate marker for HR-HPV infection in cancers of the oral cavity remains controversial.
View Article and Find Full Text PDFBackground/purpose: Although some studies have shown induction of cyclooxygenase 2 (COX-2) in oral lichen planus (OLP), an association between COX-2 upregulation and OLP clinical severity has not been investigated. Therefore, we aimed to compare COX-2 expression in OLP with that in normal oral tissues, and to determine correlations between COX-2 expression and both clinical criteria and visual analog scale (VAS) scores.
Materials And Methods: COX-2 expression was studied in 25 OLP and 13 normal oral tissues by immunohistochemistry.
Article Synopsis
- - This study compared the effectiveness of cone-beam computed tomography (CBCT) and traditional bitewing images in identifying secondary caries in teeth.
- - Researchers created 120 simulated cavities in teeth, then used different imaging techniques, finding that CBCT provided significantly higher accuracy compared to bitewing images.
- - The results indicated that CBCT not only outperformed bitewing radiographs but also showed the highest accuracy when viewed in the axial plane, making it a preferable option for detecting secondary caries.
Aim: Oral lichen planus is an oral mucosal disease that affects middle-aged patients. The characteristics of oral lichen planus in Thai patients from a multicenter were studied.
Methods: Data of 533 patients from the oral medicine clinics at Chulalongkorn and Mahidol (central Thailand), Chiang Mai (northern Thailand), and Khon Kaen (northeastern Thailand) universities during 2002-2007 were analyzed.
Human immunodeficiency virus (HIV) infection remains a serious problem in northern Thailand. A high prevalence of perinatally HIV-infected children with oral candidiasis has been observed in the region. The objective of this study was to determine oral colonization of Candida spp.
View Article and Find Full Text PDFBackground: The objectives of the study were to determine the association between Epstein-Barr virus (EBV) and oral squamous cell carcinoma (OSCC), to compare the expression of p53 and Ki67 between normal oral mucosa, oral hyperkeratosis, oral pre-malignant dysplasia, and OSCC, and to determine the correlation between the expression of p53 and Ki67 in OSCC.
Methods: The expression of EBV mRNA was studied by in situ hybridization technique in 24 cases of OSCC, and the expression of p53 and Ki67 was investigated by immunohistochemical method in 19 cases of OSCC, 7 cases of oral pre-malignant dysplasia, 6 cases of oral hyperkeratosis, and 5 cases of normal oral epithelium.
Results: None of OSCC cases expressed EBV-encoded RNA (EBER) transcripts.
Recurrent aphthous ulceration (RAU) is the most common lesion of the oral mucosa. Although many factors have been postulated as etiological factors for RAU, the role of Helicobacter pylori as a causative agent of RAU remains controversial. We therefore investigated the association of H.
View Article and Find Full Text PDFThe clinical appearances of white sponge naevus may mimic other oral white lesions, including premalignant leukoplakia but, unlike leukoplakia, white sponge naevus does not have malignant potential. This article presents a case of an irregular white lesion on the oral mucosa with findings suggestive of white sponge naevus.
View Article and Find Full Text PDFBackground: Although mast cells (MCs) have been implicated in promoting angiogenesis in some malignant tumors, especially of the aerodigestive tract, little is known in oral squamous cell carcinoma (SCC).
Methods: A retrospective study was conducted to elaborate upon the correlation between MCs and tumor angiogenesis in 26 cases of oral SCC, six cases of oral pre-malignant dysplasia, 10 cases of oral hyperkeratosis, and six cases of normal oral mucosa by means of immunohistochemical technique.
Results: The MCs in all lesions and normal oral mucosa strongly expressed tryptase.