Chemical profile and biological activities of Lysiphyllum binatum (Blanco) de Wit.

Lysiphyllum binatum (Blanco) de Wit in the Fabaceae family, despite its traditional medicinal uses, has not been the subject of prior scientific inquiry into its chemical and biological profile. The dichloromethane and MeOH extracts of its roots exhibited notably similar antioxidant activity, while the dichloromethane extract of the vine stems showed aromatase inhibition. This study aimed to identify the bioactive components responsible for these activities.

Acetogenins from the stems of Uvaria micrantha showing antiproliferative effects on HepG2 liver cancer cells.

Five mono-tetrahydrofuran acetogenins: uvamicranins A-E and three known mono-tetrahydrofuran acetogenins; reticulatacin, calamistrin A, and uvarigrin, were isolated from the stems of Uvaria micrantha (Annonaceae). Their structures were elucidated by 2D NMR and high-resolution mass spectral analysis. The absolute configurations of uvamicranins A and B were determined by modified Mosher's method.

Ent-abietane diterpenoid lactone glycosides and a phenolic glycoside from Phlogacanthus pulcherrimus T. Anderson with cytotoxic and cancer chemopreventive activities.

Nine undescribed ent-abietane diterpenoid lactone glycosides, pulcherrimosides A-I, and a phenolic glycoside, phlogoside A, together with ten known compounds were isolated from the aerial parts of Phlogacanthus pulcherrimus T. Anderson. Their structures were established through spectral methods, especially 2D NMR and HRESIMS analyses, and by acid hydrolysis.

Uvarmicranones A and B, two new benzoquinones and cytotoxic constituents from the stems of (A. DC.) Hook. f. & Thomson.

Two novel benzoquinones, uvarmicranones A () and B (), along with 15 known compounds (-) were isolated from the stems of (Annonaceae). Their structures were elucidated by analyses of NMR and high-resolution mass data. A plausible biosynthetic pathway of uvarmicranone A () Diels-Alder cycloaddition reaction was also proposed.