Can conformational flexibility influence the self-assembly behavior and sensing efficacy of fluorogenic amphiphiles? A case study with bisbenzimidazole-based probes.

In this work, we have explored the metal ion sensing properties of two bisbenzimidazole-based fluorescent probes, that differ in their conformational flexibility, in an aqueous medium. The compound with a flexible methyl spacer (1) experienced blue shifts in its absorption and emission maxima (along with a turn-off response) upon the addition of Hg ions. On the contrary, the compound with a relatively rigid structure (2) showed red shifts in both its absorption and emission maxima (along with a turn-off response) when treated with Hg under similar conditions.

Modulation in the charge transfer characteristics of flexible bis-benzimidazole probes: independent sensing mechanisms for Hg and F.

Flexible bis-benzimidazole-based V-shaped amphiphilic probes (1 and 2) that form a fluorescent nanoscopic assembly in aqueous media have been designed. The ion-binding properties of compound 1 are investigated in both polar protic (water) and aprotic (acetonitrile) solvents. In acetonitrile, the compound shows a distinct chromogenic response towards Hg (LOD: 8.

Primordial Molecular 1-Bit Magnitude Comparator in Consort with Excitation-Guided Mouldable Logic Systems: A Guided Design of Regular Interactions between Molecules.

In addition to designing certain excitation modulated logic systems, we have created the first-ever genuine molecular 1-bit magnitude comparator, using acid and base guided varied absorption responses at separate channels. Designed and manufactured Bifunctional Bis(indolyl)methane Derivative (1) demonstrates distinct optical responses (in UV-visible and fluorescence mode) to a range of chemical stimuli (acid, base, Hg, Cu, EDTA, GSH, etc.) in aqueous medium.