Publications by authors named "Suradi Wangsamuda"

Malaria in eastern Indonesia remains high despite significant reduction and elimination in other parts of the country. A rapid entomological assessment was conducted in eight high malaria endemic regencies of Papua Province, Indonesia, to expedite malaria elimination efforts in this region. This study aims to characterize specific, actionable endpoints toward understanding where and when malaria transmission is happening, where interventions may function best, and identify gaps in protection that result in continued transmission.

View Article and Find Full Text PDF
Article Synopsis
  • Dihydroartemisinin-piperaquine has been effective against uncomplicated Plasmodium falciparum malaria in Indonesia, but there's a slight increase in late treatment failures over time despite no artemisinin resistance observed.
  • The research analyzed blood samples from malaria patients to investigate genetic markers for drug resistance, finding new SNPs but no SNPs linked to artemisinin resistance, and low levels of piperaquine resistance mutations.
  • The findings suggest ongoing efficacy of the treatment, with most late failures attributed to reinfections rather than treatment failure, indicating that while resistance is not a major concern, continued monitoring is essential.
View Article and Find Full Text PDF

Background: Indonesia is home to many species of non-human primates (NHPs). Deforestation, which is still ongoing in Indonesia, has substantially reduced the habitat of NHPs in the republic. This has led to an intensification of interactions between NHPs and humans, which opens up the possibility of pathogen spillover.

View Article and Find Full Text PDF

Background: The recent deforestation for agricultural, mining, and human re-settlement has significantly reduced the habitat of many non-human primates (NHPs) in Indonesia and intensifies interaction between the NHPs and humans and thus opening the possibility of pathogen spill-over. The emergence of zoonotic malaria, such as Plasmodium knowlesi, poses an immense threat to the current malaria control and elimination that aims for the global elimination of malaria by 2030. As malaria in humans and NHPs is transmitted by the female Anopheles mosquito, malaria vector control is very important to mitigate the spill-over of the malaria parasite to humans.

View Article and Find Full Text PDF
Article Synopsis
  • Dihydroartemisinin-piperaquine (DHA-PPQ) has been used as the primary treatment for uncomplicated falciparum malaria in Indonesia since 2010, and its efficacy was assessed in two districts from April 2017 to April 2018.
  • The study involved monitoring clinical and parasitological data over 42 days for patients treated with DHA-PPQ, following World Health Organization protocols, with 114 falciparum and 81 vivax cases eventually enrolled.
  • Results showed a high efficacy of DHA-PPQ, with 93.1% of falciparum cases and 88.8% of vivax cases classified as adequately responding to treatment, with no significant delays in parasite clearance
View Article and Find Full Text PDF

Lead is one of ten hazardous chemicals of public health concern and is used in more than 900 occupations, including the battery, smelting, and mining industries. Lead toxicity accounts for 1.5% (900,000) of deaths annually in the world.

View Article and Find Full Text PDF

Background: The Indonesian archipelago is endemic for malaria. Although Plasmodium falciparum and P. vivax are the most common causes for malaria cases, P.

View Article and Find Full Text PDF

Background: The decline in intensity of malaria transmission in many areas now emphasizes greater importance of understanding the epidemiology of low to moderate transmission settings. Marked heterogeneity in infection risk within these populations creates opportunities to understand transmission and guide resource allocation to greater impact.

Methods: In this study, we examined spatial patterns of malaria transmission in a hypo- to meso-endemic area of eastern Indonesia using malaria prevalence data collected from a cross-sectional socio-demographic and parasitological survey conducted from August to November 2010.

View Article and Find Full Text PDF

Background: Sabang Municipality, in Aceh Province, Indonesia, plans to initiate a malaria elimination programme in 2013. A baseline survey of the distribution of malaria in the municipality was conducted to lay the foundations for an evidence-based programme and to assess the island's readiness to begin the elimination process.

Methods: The entire population of the municipality was screened for malaria infection and G6PD deficiency.

View Article and Find Full Text PDF