Mechanism-Guided Design of Chain-Growth Click Polymerization Based on a Thiol-Michael Reaction.

The development of chain-growth click polymerization is challenging yet desirable in modern polymer chemistry. In this work, we reported a novel chain-growth click polymerization based on the thiol-Michael reaction. This polymerization could be performed efficiently under ambient conditions and spatiotemporally regulated by ultraviolet light, allowing the synthesis of sulfur-containing polymers in excellent yields and high molecular weights.

Tadpole-like Unimolecular Nanomotor with Sub-100 nm Size Swims in a Tumor Microenvironment Model.

Inspired by the natural motors capable of performing multiple tasks in complex living environments, synthetic nanomotors emerge as a potential vehicle for revolutionizing biomedical processes. Yet current motors suffer from decreased and even completely hindered motion in a complex physiological environment, shadowing the future of this booming field. To address this problem, a unimolecular nanomotor based on molecular bottlebrush (MBB) of sub-100 nm size is reported.