Long non-coding RNA LINC00616 promotes ferroptosis of periodontal ligament stem cells via the microRNA-370 / transferrin receptor axis.

This study was designed to explore the role of lncRNA LINC00616 in the regulation of periodontitis. Cellular functions were measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assays. The content of reactive oxygen species, Fe, glutathione, and malondialdehyde were measured to determine ferroptosis in lipopolysaccharide (LPS-PG) treated periodontal ligament stem cells (PDLSCs), as well as expression of glutathione peroxidase 4 (GPX4), solute carrier family 7 member 11, and acyl-CoA synthetase long-chain family member 4 proteins mRNA and miRNA levels were measured by quantitative reverse-transcription polymerase chain reaction (qRT-PCR).

Effect of adenoid hypertrophy on the upper airway and craniomaxillofacial region.

Background: In recent years, annual incidences of adenoid hypertrophy (AH), a highly common tissue lesion in children, have increased. Currently, research on AH has focused on its obstruction of nasal cavity function, and little has been written on its influence on the upper airway's bone structure. For this reason, our present study seeks to determine the influence of AH on both the morphological development characteristics of the upper airway and the craniofacial features in children, with the goal being to offer more choices for diagnosing and treating the condition in the future.

Evaluation of IL-1β and TNF-α expression and periodontitis under the influence of orthodontic appliances with minocycline.

The current experiment was carried out to observe and analyze the effects of three orthodontic appliances combined with minocycline on periodontitis and inflammatory factors of gingival crevicular fluid. the patients included in this study were 180 patients with dental crowding treated in our hospital. They were divided into three groups, namely the invisible orthodontic appliance group (n=60), self-ligation orthodontic appliance group (n=60), traditional ligation bracket group (n=60), all of which were applied with minocycline therapy.

[Cone-beam computed tomography evaluation of short- and long-term airway changes in patients with skeletal Class Ⅲ malocclusion treated by orthodontic therapy and bimaxillary surgery with or without mandibular setback surgery].

Purpose: To evaluate the short-term and long-term effects of pharyngeal airway in skeletal Class Ⅲ malocclusion patients who underwent bimaxillary surgery or isolated mandibular setback-orthodontic treatment.

Methods: The sample included 54 patients (28 males, 26 females) who were diagnosed with skeletal Class Ⅲ malocclusion. Patents in group A (n=28) underwent mandibular setback surgery and orthodontic treatment.

[Cone-beam computed tomography evaluation of upper airway change in skeletal Class III patients after orthodontic-mandibular setback surgery].

Objective: To evaluate the short-term and long-term effects of pharyngeal airway in mandibular prognathism patients after the combined orthodontic and orthognathic treatment.

Methods: The sample included 28 skeletal Class III patients (13 males, 15 females) who had undergone mandibular setback surgery and orthodontic treatment. Cone-beam CT was taken one week before treatment (T0), 6 months (T1) and 3 years after surgery (T2).

[Cone-beam CT evaluation of nasomaxillary complex and upper airway following rapid maxillary expansion].

Objectives: To evaluate the naso-maxillary complex width and pharyngeal airway volume changes after rapid maxillary expansion (RME).

Methods: Thirty-five patients were selected (18 males, 17 females, mean age, 12.1 ± 1.

[Detection to changes in hyoid and tongue positions, and pharyngeal airway following mandibular setback surgery by cone beam CT].

Objective: To observe changes in tongue and hyoid position, and pharyngeal airway in patients with skeletal class III malocclusion after the combined orthodontic and orthognathic treatment.

Methods: Twenty patients were involved in this study. Cone beam CT (CBCT) was performed on patients one week before and six months after treatment.

[Three-dimensional analysis of pharyngeal airway in skeletal Class III patients after sagittal split ramus osteotomy].

Objective: To analyze the three-dimensional changes of pharyngeal airway in patients with skeletal Class III malocclusion after the combined orthodontic and orthognathic treatment.

Methods: Twenty patients (9 males, 11 females) and 40 subjects with normal occlusion were involved in the study. Cone-beam computed tomography (CBCT) were performed on patients one week and six months after treatment.