Uric acid as a cardiorenal mediator: pathogenesis and mechanistic insights.

: The role of serum uric acid as a connector in cardiorenal interactions has been long debated and studied extensively in the past decade. Epidemiological, and clinical data suggest that hyperuricemia may be an independent risk factor as well as a strong predictor of morbidity and mortality in cardiovascular diseases (CVD) and renal diseases. New data suggesting that urate lowering therapies may improve outcomes in cardiovascular diseases have generated interest.

Gastric carcinoma and acute myeloid leukemia: A case report of a double malignancy.

A double malignancy involving a solid organ and hematopoieteic system is rare. We report an interesting case of gastric adenocarcinoma with subsequent development of acute myeloid leukemia, in the absence of any therapeutic intervention.

Predictors of over-the-counter medication: A cross-sectional Indian study.

Context: The determinants of over-the-counter (OTC) medication need to be understood to design adequate drug information policies.

Aim: To determine the prevalence and predictors of OTC medication among the adult population of Berhampur town in Odisha, India.

Settings And Design: It was a prospective, cross-sectional, observational study carried out in the private retail pharmacy on a convenience sample of 880 adults over a period of 6 months at Berhampur, Odisha, India.

Drug-related problems associated with self-medication and medication guided by prescription: A pharmacy-based survey.

Objectives: The objective of this study is to identify and compare the nature of the drug-related problems (DRPs) associated with self-medication and non-self-medication (drug use guided by a prescription).

Materials And Methods: The cross-sectional, observational study was conducted on 1100 adult participants at a convenience sample of six retail private pharmacy counters. The data collection form was based on the Pharmaceutical Care Network Europe version 6.

Effect of aqueous extract of Aegle marmelos unripe fruit on inflammatory bowel disease.

Objective: The present study was designed to evaluate the effect of Aegle marmelos unripe fruit extract (AMFE) on inflammatory bowel disease (IBD) in Wistar albino rats.

Materials And Methods: Effect of AMFE was studied on acetic acid induced ulcerative colitis (1 ml of 4% acetic acid solution, transrectal) and indomethacin-induced enterocolitis (10 mg/kg, single dose, p.o) in Wistar albino rats.