Structural insights to the RRM-domain of the glycine-rich RNA-binding protein from Sorghum bicolor and its role in cold stress tolerance in E. coli.

Sorghum bicolor Glycine-rich RNA-binding protein (SbGRBP), exhibit the ability to bind both single-stranded and double-stranded DNA. The expression of SbGRBP is regulated by heat stress, with the protein localizing to the nucleus and cytosol. The present study delves into the structure and ssDNA binding ability of its truncated version (SbGRBP1-119) which lacks glycine rich domain (GR).

, , : Up-conversion in Lead Borophosphate Glasses for Visible Emission.

To investigate the role of PbO as a former or a modifier and effect of its compositional variation on the physical, structural and optical properties, lithium lead borophosphate glasses were synthesized by melt quenching technique. For the physical properties of the prepared glasses, density was measured using the Archimedes principle, which showed an increasing trend from 3.13 to 4.

An efficient multi-level thresholding method for breast thermograms analysis based on an improved BWO algorithm.

Breast cancer is a prevalent disease and the second leading cause of death in women globally. Various imaging techniques, including mammography, ultrasonography, X-ray, and magnetic resonance, are employed for detection. Thermography shows significant promise for early breast disease detection, offering advantages such as being non-ionizing, non-invasive, cost-effective, and providing real-time results.

The Impact of Frailty on Outcomes of Proximal Aortic Aneurysm Surgery: A Nationwide Analysis.

(1) Background: This study examines frailty's impact on proximal aortic surgery outcomes. (2) Methods: All patients with a thoracic aortic aneurysm who underwent aortic root, ascending aorta, or arch surgery from the 2016-2017 National Inpatient Sample were included. Frailty was defined by the Adjusted Clinical Groups Frailty Indicator.

A self-adaptive attraction and repulsion-based naked mole-rat algorithm for energy-efficient mobile wireless sensor networks.

Naked mole-rat algorithm (NMRA) is a swarm intelligence-based algorithm that draws inspiration from the mating behaviour of mole rats (workers and breeders). This approach, which is based on the ability of breeders to reproduce with the queen, has been utilized to tackle optimization problems. The algorithm, however, suffers from local optima stagnation problem and a slower rate of convergence in order to provide gobal optimal solution.

Giant Cell Tumor: A Case Series of Seven Patients with GCT at Atypical Sites.

Introduction: Giant cell tumor (GCT) represents 5% of all primary bone tumors and 20% of biopsy analyzed benign tumors. More than half of these lesions occur in the 3rd and 4th decades of life. There is no absolute treatment method selection.

Characterization and regulation of salt upregulated cyclophilin from a halotolerant strain of Penicillium oxalicum.

Penicillium species are an industrially important group of fungi. Cyclophilins are ubiquitous proteins and several members of this family exhibit peptidyl-prolyl cis-trans isomerase (PPIase) activity. We had earlier demonstrated that the salt-induced PPIase activity in a halotolerant strain of P.

Validation of American Society of Echocardiography Guideline-Recommended Parameters of Right Ventricular Dysfunction Using Artificial Intelligence Compared With Cardiac Magnetic Resonance Imaging.

Background: Right ventricular (RV) function is important in the evaluation of cardiac function, but its assessment using standard transthoracic echocardiography (TTE) remains challenging. Cardiac magnetic resonance imaging (CMR) is considered the gold standard. The American Society of Echocardiography recommends surrogate measures of RV function and RV ejection fraction (RVEF) by TTE, including fractional area change (FAC), free wall strain (FWS), and tricuspid annular planar systolic excursion (TAPSE), but they require technical expertise in acquisition and quantification.

Aortic root management in acute type A aortic dissection: A nationwide analysis.

Objective: Acute type A aortic dissection (ATAAD) is a life-threatening condition and surgical repair often includes aortic valve replacement (AVR). Aortic valve repair (AVr) is increasingly being reported with favorable outcomes from single-center experiences. This study examined national trends and outcomes of AVr in patients with ATAAD.

Debunking the July Effect in Transcatheter Interventions in Structural Heart Disease: Truth or Myth?

Background: The "July effect", the perception of worse outcomes in the first month of training, has been previously demonstrated in critical care medicine and general surgery. However, the July effect in the context of structural heart interventions (i.e.

OsCyp2-P, an auxin-responsive cyclophilin, regulates Ca calmodulin interaction for an ion-mediated stress response in rice.

OsCYP2-P is an active cyclophilin (having peptidyl-prolyl cis/trans-isomerase activity, PPIase) isolated from the wild rice Pokkali having a natural capacity to grow and yield seeds in coastal saline regions of India. Transcript abundance analysis in rice seedlings showed the gene is inducible by multiple stresses, including salinity, drought, high temperature, and heavy metals. To dissect the role of OsCYP2-P gene in stress response, we raised overexpression (OE) and knockdown (KD) transgenic rice plants with >2-3 folds higher and approximately 2-fold lower PPIase activity, respectively.

The Effect of Social Determinants and Socioeconomic Status on Laparoscopic Roux-En-Y Gastric Bypass for Weight Loss: An Analysis of the National Inpatient Sample.

 In the United States, Black and Hispanic patients have a higher prevalence of obesity than Whites (49.6 vs. 44.

Socioeconomic risk factors for mortality and readmission after surgery for bowel obstruction: An analysis of the Nationwide Readmissions Database.

Background: Small bowel obstructions (SBO) are one of the most common surgical emergencies, but they remain a major cause of high morbidity and mortality in patients with previous history of abdominal and pelvic surgery. Socioeconomic factors have not been extensively studied in surgical management of SBO.

Methods: We queried the 2016 NRD database for all surgically managed admissions ≥18 years of age with a primary diagnosis of SBO.

Treatment of Acute Cholecystitis at Safety-Net Hospitals: Analysis of the National Inpatient Sample.

Evidence supports index cholecystectomy as the quality of care for patients admitted with acute cholecystitis. We sought to examine the role of hospital safety-net status on whether patients received appropriate index procedures for cholecystitis. The National Inpatient Sample was queried for patients with acute cholecystitis.

A Propensity Score-Matched Analysis of Laparoscopic versus Open Surgery in Patients with COPD.

: This study aims to compare outcomes of laparoscopic surgery to the outcomes of open surgery in patients with chronic obstructive pulmonary disease (COPD). Plethora of studies compares laparoscopic and open surgery in the general population; however, there is a paucity of existing literature examining the optimal surgical techniques in the COPD population. : A propensity score-matched analysis using the 2012-2015 National Inpatient Sample (NIS) was conducted to match COPD patients undergoing the most common laparoscopic procedures to COPD patients undergoing the same procedures through an open approach.

Colonoscopy utilization in rural areas by general surgeons: An analysis of the National Ambulatory Medical Care Survey.

Background: One in three adults above 50 years old have not been screened for colorectal cancer as of 2013. Rural areas have even lower screening and have more general surgeons compared to gastroenterologists, offering surgeons as a reservoir for necessary services.

Methods: Public data from the 2006-2015 CDC National Ambulatory Medical Care Survey was analyzed using SAS.

Acute Endophthalmitis Caused by spp. following Intravitreal Bevacizumab Injection.

We present a case of acute endophthalmitis caused by spp. following intravitreal bevacizumab injection. An 86-year-old immunocompetent female developed acute endophthalmitis after intravitreal injection of bevacizumab for neovascular age-related macular degeneration.

A temperature-responsive gene in sorghum encodes a glycine-rich protein that interacts with calmodulin.

Imposition of different biotic and abiotic stress conditions results in an increase in intracellular levels of Ca which is sensed by various sensor proteins. Calmodulin (CaM) is one of the best studied transducers of Ca signals. CaM undergoes conformational changes upon binding to Ca and interacts with different types of proteins, thereby, regulating their activities.

The peptidyl-prolyl isomerase activity of the wheat cyclophilin, TaCypA-1, is essential for inducing thermotolerance in .

Growth at high temperatures is one of the desired features for industrial applications of microbes, as it results in decrease in contamination and enhanced solubility of certain substrates. In this study, it is demonstrated that heterologous expression of a wheat cyclophilin, TaCypA-1, confers thermotolerance to . The TaCypA-1 possesses peptidyl-prolyl isomerase (PPIase) activity that catalyses to isomerization of the peptidyl prolyl bonds, a rate limiting step in protein folding.

Laryngopyocele: Presenting with pressure symptom.

Laryngocele is a rare, benign dilatation of the laryngeal saccule that may extend internally into the airway or externally through the thyrohyoid membrane. When it is secondarily infected, it is called laryngopyocele, which is even rarer. Many laryngoceles are asymptomatic; sometimes, they may cause a cough, hoarseness, stridor, sore throat and may present as a swelling on one or both sides of the neck.

Abiotic stress responses in plants: roles of calmodulin-regulated proteins.

Intracellular changes in calcium ions (Ca(2+)) in response to different biotic and abiotic stimuli are detected by various sensor proteins in the plant cell. Calmodulin (CaM) is one of the most extensively studied Ca(2+)-sensing proteins and has been shown to be involved in transduction of Ca(2+) signals. After interacting with Ca(2+), CaM undergoes conformational change and influences the activities of a diverse range of CaM-binding proteins.