Purpose: To compare variance of manifest refraction (MR) measurement and variance of refractive outcomes after keratorefractive lenticule extraction (KLEx) in the same cohort.
Methods: This was a retrospective study of consecutive patients attending at least three preoperative refractions before undergoing KLEx. All manifest refractions were performed according to a standard protocol.
Purpose: To evaluate the impact of refractive couplings in myopia and myopic astigmatism with two different keratorefractive lenticule extraction (KLEx) systems.
Methods: This was a retrospective evaluation of refractive outcomes with two different lasers studying 2,841 eyes undergoing small incision lenticule extraction (SMILE) (VisuMax 500; Carl Zeiss Meditec) and 2,528 eyes undergoing SmartSight (ATOS; SCHWIND eye-tech-solutions GmbH). Coupling effects (derived from the ratio between partial slopes) were determined for sphere and cylinder and for spherical equivalent, cardinal, and oblique astigmatism separately.
Purpose: Assessing the applicability of an algorithm developed for keratoconus detection in adolescents. This algorithm relies on optical coherence tomography (OCT) and incorporates features related to corneal pachymetric and epithelial thickness alterations.
Methods: We retrospectively reviewed charts of patients under the age of 18 and divided them into four groups according to the Belin-Ambrosio display (Pentacam): normal, manifest, and subclinical keratoconus, as well as very asymmetric eye with normal topography and tomography (VAE-NTT).
Purpose: To identify potential risk factors that increase the likelihood of re-treatment following keratorefractive lenticule extraction (KLEx) for myopia and myopic astigmatism.
Methods: This was a retrospective study of patients with myopia and myopic astigmatism who underwent KLEx using the VisuMax 500 laser (Carl Zeiss Meditec) between April 2015 and December 2020. Patients were assigned to one of two groups: the control group and the re-treatment group (if they had additional refractive surgery within 2 years of the primary treatment).
Purpose: To compare the effects of corneal allogenic intrastromal ring segment (CAIRS) implantation on topographical measurements and visual outcomes of patients with keratoconus with and without corneal cross-linking (CXL) prior to the time of implantation.
Methods: Sixty-seven eyes with corneal allograft intrastromal ring segment implantation (KeraNatural; Lions VisionGift) due to advanced keratoconus were included in the study. Thirty-seven eyes had no CXL and 30 eyes had had CXL before being referred to the authors.
Background: Achieving precise refractive outcomes in phakic posterior chamber intraocular lens (pIOL) implantation is crucial for patient satisfaction. This study investigates factors affecting pIOL power calculations, focusing on myopic eyes, and evaluates the potential benefits of advanced predictive models.
Design: Retrospective, single-center, algorithm improvement study.
Objective: To assess the performance of convolutional neural networks (CNNs) for automated detection of keratoconus (KC) in standalone Scheimpflug-based dynamic corneal deformation videos.
Design: Retrospective cohort study.
Participants: We retrospectively analyzed datasets with records of 734 nonconsecutive, refractive surgery candidates, and patients with unilateral or bilateral KC.
Purpose: To investigate the influence of lenticule extraction on subjective symptoms and objective biomarkers of dry eye and to clarify relationships between markers and find indicators for subjective symptoms after lenticule extraction.
Methods: Right eyes of myopic patients undergoing lenticule extraction surgery (n = 35) were examined preoperatively and 5 and 90 days postoperatively using established clinical dry eye examination methods (tear film break-up time [BUT], Schirmer test, lissamine green and fluorescein staining, and Ocular Surface Disease Index (OSDI) questionnaire). A patient subset was also examined after 1 year (n = 14).
Purpose: To demonstrate the safety and efficacy of allogenic corneal inlays designed to increase the depth of focus (DoF) in treated eyes.
Settings: Medipol University Hospital, Istanbul, Turkey.
Design: Prospective case series.
Purpose: To compare clinical outcomes and rotational stability of the toric implantable Collamer lens (TICL) and toric implantable phakic contact lens (TIPCL).
Methods: Charts were reviewed from January 2011 to January 2023 to identify all TICLs and TIPCLs implanted by a single surgeon. Implant size was generally chosen according to the manufacturer's recommendation, but 15 TIPCLs 0.
Background: To evaluate the safety and efficacy of corneal allogenic intrastromal ring segments in the management of keratoconus patients.
Methods: The retrospective, nonrandomized, interventional case series consisted of 65 keratoconic eyes of 49 consecutive patients who had ring segment-shaped corneal allografts (KeraNatural®) implanted in intrastromal tunnels created using a femtosecond laser. The main outcome measures were uncorrected visual acuity (UCVA), corrected distant visual acuity (CDVA), refraction, keratometry, and pachymetry.
Objective: To assess the performance of convolutional neural networks (CNNs) for automated diagnosis of dry eye (DE) in patients undergoing video keratoscopy based on single ocular surface video frames.
Design: This retrospective cohort study included 244 ocular surface videos from 244 eyes of 244 subjects based on corneal topography. A total of 116 eyes were normal while 128 eyes had DE based on clinical evaluations.
Purpose: To optimize artificial intelligence (AI) algorithms to integrate Scheimpflug-based corneal tomography and biomechanics to enhance ectasia detection.
Design: Multicenter cross-sectional case-control retrospective study.
Methods: A total of 3886 unoperated eyes from 3412 patients had Pentacam and Corvis ST (Oculus Optikgeräte GmbH) examinations.
Femtosecond laser-assisted in situ keratomileusis (Femto-LASIK) represents a common treatment modality in refractive surgery and shows excellent results in terms of safety, efficacy, predictability, and long-term stability. However, patients may be affected by dry eye symptoms. The aim of this study was to identify a potential association between subjective dry eye symptoms, objective dry eye markers, and possible changes in the tear film, which could be a target for future therapy development.
View Article and Find Full Text PDFPurpose: Evaluation of mRNA and microRNA (miRNA) expression in epithelium and stroma of patients with keratoconus.
Methods: The epithelium and stroma of eight corneas of eight patients with keratoconus and eight corneas of eight non-keratoconus healthy controls were studied separately. RNA was extracted, and mRNA and miRNA analyses were performed using microarrays.
J Cataract Refract Surg
December 2022
Purpose: To detect keratoconus (KC) only by analyzing the corneal and epithelial map parameters and patterns in optical coherence tomography (OCT).
Setting: Tertiary care refractive surgery center.
Design: Retrospective data collection.
Graefes Arch Clin Exp Ophthalmol
May 2022
Purpose: The purpose of this study is to document clinical outcomes of 2 posterior chamber phakic intraocular lenses with a central hole, the implantable contact lens (IPCL V2.0) and the Visian implantable collamer lens V4c (ICL), in myopic and myopic-astigmatic patients.
Methods: Retrospective study comprising 111 IPCL (60 toric) and 106 ICL implantations (59 toric) with a follow-up of 3 months to 2 years.
Background: Patients and refractive surgeons have a legitimate interest in the long-term results of the most commonly used laser procedures for correction of ametropia.
Objective: To assess the safety, predictability, stability and late complications according to the current recommendations of the committee for refractive surgery (KRC).
Methods: Literature search in PubMed with the search term "long-term outcome" combined with either "PRK", "LASIK" or "SMILE".
Purpose: To validate and evaluate the use of a new biomechanical index known as the Corvis biomechanical index-laser vision correction (CBI-LVC) as a method for separating stable post-LVC eyes from post-LVC eyes with ectasia.
Setting: 10 clinics from 9 countries.
Design: Retrospective, multicenter, clinical study.
Purpose: In Epi-Bowman Keratectomy™ (EBK), a new dynamic multi-blade single-use device (Epi-Clear™, Orca Surgical, Israel) is utilized to remove the epithelium by sweeping movements across the corneal surface. Epithelial cells are discarded. Alcohol or other chemical agents are not utilized.
View Article and Find Full Text PDFPurpose: To evaluate the intraexaminer repeatability and the interobserver reproducibility of manifest refraction.
Setting: Tertiary referral center.
Design: Retrospective study.
Purpose: To evaluate the influence of a thin cap in small-incision lenticule extraction (SMILE) for the correction of myopia or myopic astigmatism.
Setting: Tertiary care private practice.
Methods: A chart review of 102 eyes of 51 patients was performed.