Clinical features and outcomes of delayed-onset primary cytomegalovirus disease in cardiac transplant recipients.

Background: Cytomegalovirus (CMV)-seronegative recipients of cardiac allografts from CMV-seropositive donors (CMV D(+)/R(-)) are at highest risk of CMV disease after transplantation. This study was conducted to investigate the incidence, clinical features, risk factors and outcome of delayed-onset primary CMV disease in cardiac recipients who received anti-CMV prophylaxis.

Methods: This study enrolled all CMV D(+)/R(-) cardiac recipients during the period from 2000 to 2004.