Farmers' adaptation to climate change in Pakistan: Can their climate risk management strategies lead to sustainable agriculture?

Farming communities in many developing nations are facing the impacts of climate change, characterized by greater variability and frequency of extreme weather events, which threaten their livelihoods and the agricultural sector as a whole. Agricultural sustainability is at risk when farmers engage in off-farm activities to protect their economic future and combat climate change. This study aimed to identify the determinants of off-farm management activities adoption and highlight the issues faced by farmers after their adoption in agriculture.

Epidemiological and economic consequences of lumpy skin disease outbreaks on farm households in Khyber Pakhtunkhwa, Pakistan.

The livestock sector plays a crucial role in sustaining the livelihoods of millions of families across the world, especially in developing countries. However, farming households that rely on agriculture and livestock are particularly susceptible to the impacts of various infectious diseases and natural disasters. This study focuses on estimating the economic burden imposed on households by lumpy skin disease (LSD) in Pakistan and explores the effect of various socioeconomic factors on mortality ratio.

Higher education institutions, SDG2 and agri-food sustainability: lessons from Chulalongkorn University and Thailand.

This paper examines higher education efforts linking United Nations Sustainable Development Goals (UNSDGs) and agri-food system sustainability given reports of stagnant movement for SDG2 in Southeast Asia and lack of data for effective monitoring or evaluation to realize the . It discusses Thai contexts amid a growing global movement in academic theory, policy and practice to mainstream SDG knowledge and implementation across campuses presenting one case to illustrate broader concerns. Chulalongkorn University policies, faculty awareness, curricula, research, sustainability reporting and partnerships about SDGs have contributed to SDG2 objectives from different disciplines and academic units.

Serum antibodies and cytokines in C4-deficient mice and their responses to exercise.

Psychological stress is believed to be one of the predisposing factors for systemic lupus erythematosus (SLE), whereas physical stress such as exercise has never been reported to be related. We measured the circulating levels of antibodies (IgM, IgG, anti-dsDNA IgG), Th1 (IFN-gamma), Th2 (IL-4, IL-6), and of pro-inflammatory (TNF-alpha, IL-1beta) and anti-inflammatory (TGF-beta) cytokines of C4(-l-) female mice at rest, after acute exercise and after exercise training, using an antibody-capture ELISA. Prior to the exercise, the C4(-l-) mice had higher levels of IgG and anti-dsDNA IgG but lower levels of IFN-gamma, IL-1beta, IL-6 and IL-4 than wild-type C57BL/6 (B6) mice.

Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.

Hypomorphic mutations in DNA ligase IV (LIG4) cause a human syndrome of immunodeficiency, radiosensitivity, and growth retardation due to defective DNA repair by the nonhomologous end-joining (NHEJ) pathway. Lig4-null mice are embryonic lethal, and better mouse models are needed to study human LigIV syndrome. We recently identified a viable mouse strain with a Y288C hypomorphic mutation in the Lig4 gene.