Association of polymorphisms in proinflammatory cytokine genes with the development of oral cancer in Southern Thailand.

Oral squamous cell carcinoma (OSCC) is highly prevalent in southeastern Asia suggesting that region-specific environmental and biological factors contribute to the development of this cancer. Exposure to oral carcinogens (i.e.

Polymorphism in DNA repair genes and oral squamous cell carcinoma in Thailand.

DNA repair capacity is essential in maintaining cellular functions and homeostasis. However, the repair capacity can be altered based on DNA sequence variations in DNA repair genes and thus may cause cancer susceptibility. We investigated associations between polymorphisms in DNA repair genes and oral squamous cell carcinoma (OSCC) in a Thai population.

Formulation and efficacy of triamcinolone acetonide mouthwash for treating oral lichen planus.

Purpose: The stability of a triamcinolone acetonide mouthwash and its efficacy in treating oral lichen planus are described.

Methods: The solubility of triamcinolone acetonide in ethanol, propylene glycol, and glycerin was determined by shaking and equilibrating an excess of triamcinolone acetonide with the solvents for 72 hours. All three solvents were used in formulating a mouthwash.

The p53 codon 72 polymorphism and risk of oral cancer in Southern Thailand.

The codon 72 polymorphism of the p53 tumor suppressor gene has been investigated extensively for its association with various cancers around the world. However, its influence has not been elucidated in the Thai population. Therefore, a case-control study with 97 patients and 97 matched controls was conducted to elucidate the association between the polymorphic p53 and oral cancer risk in a Southern Thai population.

High tumor necrosis factor-alpha levels in the patients with Epstein-Barr virus-associated peripheral T-cell proliferative disease/lymphoma.

We have attempted to find out any relationships between circulating tumor necrosis factor (TNF)-alpha levels and Epstein-Barr virus (EBV) associated peripheral T-cell and NK-cell proliferative disease/lymphoma (PTPD/L) status. The distribution of TNF-alpha level was significantly higher (P<0.05) in patients than in controls.