Publications by authors named "SuoChao Fu"

Objective: Autologous iliac bone is commonly used as a bone graft material to achieve solid fusion in craniocervical junction (CVJ) surgery. However, the developing iliac bone of children is less than ideal as a bone graft material. The matured rib bone of children presents a potential substitute material for iliac bone.

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Study Design: Retrospective study.

Objective: To classify surgical failures following atlantoaxial dislocation, present strategies for revisions, and evaluate the clinical results of revision surgery.

Summary Of Background Data: With the increase in atlantoaxial dislocation surgery, the number of surgical failures has gradually risen.

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Backgrounds: This study aimed to compare whether Calcium phosphate cement (CPC) promotes the stability of osteoporotic lumbar pedicle screw by enhancer-injecters with different number of holes.

Methods: Through a self-designed bone cement injection device, the pedicle screw canal was strengthened with calcium phosphate bone cement, and divided into 4-hole group, 6-hole group, 8-hole group, straight pore group and the control group. The screw was inserted into the mechanical test module, the Maximum insertion torque and Maximum axial pull-out strength were recorded, and the distribution of calcium phosphate bone cement was analyzed by CT and X-ray.

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Background: Transoral anterior C1-ring osteosynthesis has been reported as an effective treatment for unstable atlas fracture, which aims to preserve important C1-C2 motion. However, previous studies have shown that the anterior fixation plates used in this technique were not suitable for the anterior anatomy of the atlas and lacked an intraoperative reduction mechanism.

Objective: This study aims to evaluate the clinical effects of a novel reduction plate used in transoral anterior C1-ring osteosynthesis for unstable atlas fractures.

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Background: Ankylosing spondylitis-related cervical spine fracture with neurologic impairment (ASCF-NI) is a rare but often lethal injury. Factors independently associated with survival after treatment remain poorly defined, and identifying patients who are likely to survive the injury remains challenging.

Questions/purposes: (1) What factors are independently associated with survival after treatment among patients with ASCF-NI? (2) Can a nomogram be developed that is sufficiently simple for clinicians to use that can identify patients who are the most likely to survive after injury?

Methods: This retrospective study was conducted based on a multi-institutional group of patients admitted and treated at one of 29 tertiary hospitals in China between March 1, 2003, and July 31, 2019.

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Background: Currently, irreducible atlantoaxial dislocation (IAAD) can be treated by a single transoral approach in one stage to reduce surgical injuries to patients. However, the widely used fixation devices are not suitable for pediatric patients because of larger profile of devices.

Objective: The purpose of this study is to report the preliminary clinical outcomes of a novel surgical technique by transoral intraarticular cage distraction and fusion with C-JAWS staple fixation for pediatric patients with IAAD.

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Background: Irreducible atlantoaxial rotatory fixation (IAARF) often requires surgical treatment. Transoral unlocking the facet joints is a key measure for the treatment of IAARF. We investigate a novel method for treating pediatric IAARF by unlocking facet joint through transoral appraoch and fixed with slim-tarp plate in same stage with same approach.

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Article Synopsis
  • This study explores a new surgical method for treating irreducible atlantoaxial dislocation (IAAD) and basilar invagination (BI) using a transoral approach, focusing on osteotomy and plate fixation to correct bony deformities.
  • The researchers conducted the procedure on 213 patients between March 2015 and December 2019, addressing various bony factors that hindered reduction and causing symptoms like neck pain, headaches, and mobility issues.
  • Post-surgery results showed significant improvement in key measurements, with notable reductions in average anteroposterior diameter and cervical angles, alongside enhanced clinical symptoms and overall patient recovery as indicated by improved JOA scores.
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Objectives: To study the changes of bacterial flora after a series of preoperative oral disinfection and the postoperative recovery of nerve function of patients with craniovertebral junction disorders who were treated with transoral approach operations.

Methods: This research analyzed 20 cases collected from October 2009 to May 2010. All these patients were with CVJ disorders, including 8 males and 12 females, aged 2 to 66 (38.

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Background: The mortality rate in patients with ankylosing spondylitis (AS) and cervical fracture is relatively high.

Objectives: This study aimed to investigate the instantaneous death risk and conditional survival (CS) in patients with AS and cervical fracture. We also studied the relationship between surgical timing and the incidence of complications.

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Background: The study aimed to (1) create a series of pedicle injectors with different number of holes on the sheath especially for the Chinese elderly patients and (2) further investigate the effects of the injectors on the augmentation of pedicle screw among osteoporotic lumbar pedicle channel.

Methods: This study used the biomechanical test module of polyurethane (Pacific Research Laboratory Corp, USA) to simulate the mechanical properties of human osteoporotic cancellous bone. The bone cement injectors were invented based on anatomical parameters of lumbar pedicle in Chinese elderly patients.

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Objective: To investigate the method of treating tuberculosis in the craniovertebral junction and its effectiveness.

Methods: The clinical data of 18 patients with tuberculosis in the craniovertebral junction between July 2010 and January 2019 was analyzed retrospectively. There were 14 males and 4 females, aged 21 months to 75 years (median, 35 years).

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Objective: To investigate the surgical method for primary malignant osseous tumors in the craniovertebral junction (CVJ) and its effectiveness.

Methods: The clinical data of 7 patients with primary malignant osseous spinal tumors in CVJ, which collected between September 2010 and April 2019, were retrospectively analyzed. There were 5 males and 2 females, aged 23 to 75 years (median, 56 years).

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Osteoporosis is now a worldwide public health problem that seriously endangers human health, but its causes have not yet been fully clarified. Recently, increasing evidence suggested that polymorphisms in gene were associated with osteoporosis risk and bone mineral density (BMD), but results remained conflicting. We herein performed a meta-analysis based on evidence currently available from the literature to make a more precise estimation of these relationships.

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Objective: Fracture is a common consequence of osteoporosis and is associated with high morbidity and mortality. Recently, increasing evidence has suggested that polymorphisms in tumor necrosis factor-α (TNF-α) gene were associated with osteoporosis risk and bone mineral density (BMD), but results remain conflicting. We herein performed a meta-analysis based on evidence currently available from the literature to make a more precise estimation of these relationships.

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Background: Histamine H2 antagonists (H2RAs) have long been suggested to have beneficial effects on congestive heart failure (CHF). However, full agreement about the cardioprotective effects of H2RAs is still not reached yet. Therefore, this study aims to clarify the effects of H2RAs on myocardial function in CHF patients by meta-analysis.

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Article Synopsis
  • A finite element analysis was conducted to assess the effectiveness of the Ti-24Nb-4Zr-7.9Sn (Ti2448) pedicle screw system in enhancing single-level posterior lumbar interbody fusion (PLIF).
  • The Ti2448 system showed decreased axial displacement at the fusion level compared to both screw-free status and the Ti-6Al-4V system, indicating potential benefits in maintaining spinal stability.
  • The study concluded that the Ti2448 screw system could reduce intradiscal pressures at adjacent discs, suggesting it may mitigate complications associated with traditional pedicle screw systems.
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Failure of fixation caused by loosening of pedicle screws in osteoporosis is a problem in spinal surgery. We compared the in vivo fixation strength between pedicle screws treated with microarc oxidation (MAO) and untreated screws in an osteoporotic model of ovariectomized sheep. The MAO treated and untreated screws were placed in lumbar vertebral bodies.

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The incidence of osteoporosis continues to increase with progressively aging populations. The purpose of this study was to detect the effects of glucocorticoid (GC) treatment on bone mineral density (BMD), biomechanical strength and micro-architecture in cancellous and cortical bone in ovariectomized (OVX) rabbits. Twenty adult female New Zealand white rabbits were randomly divided into three groups.

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Study Design: Low elastic modulus expandable pedicle screw (L-EPS) was inserted into osteoporotic sheep. Biomechanical tests, micro-CT analysis and histologic observation were performed.

Objective: To find out whether the L-EPS can further improve fixation strength compared to the expandable pedicle screws (EPS) in osteoporotic sheep spine.

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Article Synopsis
  • Transpedicular fixation in osteoporotic spines is complicated, and this study compares the effectiveness of expansive pedicle screws (EPS) and polymethylmethacrylate-augmented pedicle screws (PMMA-PS) for screw stability.
  • The study involved 15 osteoporotic vertebrae divided into three groups: a conventional screw group, a PMMA-PS group, and an EPS group, with stability tests conducted after a day.
  • Results showed that both EPS and PMMA-PS significantly improved screw stability compared to conventional screws, with no significant difference in effectiveness between the two methods, suggesting EPS could be a preferable option for clinical use due to its advantages in avoiding common complications associated with PMMA.
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Study Design: Partial screw augmentation was carried out by the injection of polymethylmethacrylate (PMMA) through the novel tap into the bone tissue in sheep vertebrae in vitro. Biomechanical tests and microcomputerized tomography analysis were done.

Objective: To evaluate the stability of the screw and the interface between the bone and the screw in partial screw augmentation.

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Study Design: An in-vitro cadaver-based measurement using microcomputed tomography.

Objectives: To evaluate the safety of removal of expandable pedicle screws (EPSs) in human vertebral bodies after a long (6 mo) insertion time.

Summary Of Background Data: Transpedicular fixation is commonly used for posterior fixation of the spine.

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Study Design: Augmentation of pedicle screws with calcium sulfate cement (CSC) was performed in osteoporotic sheep. Biomechanical tests, micro-computed tomography (CT) analysis, and histological observation were performed.

Objective: To investigate the long-term biomechanical performance of pedicle screws augmented with CSC in vivo and evaluated the screw-bone interfacial bonding with micro-CT and histological techniques.

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