Publications by authors named "Sunqi Nian"

Background: Modic changes (MCs), vertebral end plate and bone marrow damage observed by magnetic resonance imaging, are an independent risk factor for low back pain. The compositions of and interaction between microbiota and metabolites in the lumbar cartilaginous end plates (LCEPs) of patients with MCs have not been identified.

Methods: Patients with lumbar disc degeneration who were undergoing lumbar spinal fusion surgery were recruited between April 2020 and April 2021.

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Background: Modic changes (MCs) are identified as an independent risk factor for low back pain. Different subtypes of MCs vary in their impact on postoperative pain relief. However, consensus on the transformation of postoperative MC fractions in patients with distinct MC subtypes is lacking.

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Article Synopsis
  • Osteoporosis significantly increases the risk of fractures, especially vertebral compression fractures, making accurate diagnosis essential for effective treatment in patients over 45 years old.
  • This study aimed to create a predictive model using T1 MRI images to determine osteoporosis presence in patients with lumbar compression fractures.
  • A total of 128 participants were analyzed, extracting 1906 imaging features, leading to a refined model that assesses fracture-related osteoporosis using advanced machine learning techniques.
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  • The study aimed to determine if adding ketamine to local anesthetics in regional anesthesia could extend pain relief for patients undergoing various surgeries.
  • A systematic review and meta-analysis of 20 randomized controlled trials involving 1,011 patients were conducted, focusing on surgeries like cesarean sections and orthopedic procedures.
  • Results showed that ketamine significantly prolonged the duration of analgesia (about 172 minutes on average), particularly with peripheral nerve blocks, while also monitoring for any adverse effects related to ketamine.
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Background Context: Previous low-quality evidence has suggested preoperative Modic changes (MC) showed a trend toward less improvement in low back pain in patients with lumbar disc herniation (LDH) undergoing discectomy. However, a recent meta-analysis concluded that the presence of preoperative MC did not significantly impact clinical outcomes following lumbar discectomy.

Purpose: To compare low back pain and functional outcomes of patients after discectomy for LDH with preoperative MC.

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